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Computational studies of cation-π interactions and applications to neuroscience

Dougherty, Dennis A. (2015) Computational studies of cation-π interactions and applications to neuroscience. In: 45th Western Regional Meeting of the American Chemical Society, November 6-8, 2015, San Marcos, CA. https://resolver.caltech.edu/CaltechAUTHORS:20160302-081250477

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Abstract

The cation-π interaction is important in many contexts throughout chemistry and biology. We have been particularly focused on its role in ligand recognition in neuroscience. We will show how a combination of computation and experiment has allowed us to identify key cation-π interactions in a range of neuroreceptors. We have also shown the crucial role the cation-π interaction plays in the addictive properties of nicotine.


Item Type:Conference or Workshop Item (Paper)
Related URLs:
URLURL TypeDescription
http://wrm2015.sites.acs.org/OrganizationConference Website
ORCID:
AuthorORCID
Dougherty, Dennis A.0000-0003-1464-2461
Additional Information:© 2015 American Chemical Society.
Record Number:CaltechAUTHORS:20160302-081250477
Persistent URL:https://resolver.caltech.edu/CaltechAUTHORS:20160302-081250477
Usage Policy:No commercial reproduction, distribution, display or performance rights in this work are provided.
ID Code:64948
Collection:CaltechAUTHORS
Deposited By: Tony Diaz
Deposited On:02 Mar 2016 17:13
Last Modified:03 Oct 2019 09:42

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