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Neural Crest Inducing Signals

Basch, Martín L. and Bronner-Fraser, Marianne (2006) Neural Crest Inducing Signals. In: Neural Crest Induction and Differentiation. Advances in Experimental Medicine and Biology. No.589. Springer , New York, NY, pp. 24-31. ISBN 978-0-387-35136-0.

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The formation of the neural crest has been traditionally considered a classic example of secondary induction, where signals form one tissue elicit a response in a competent responding tissue. Interactions of the neural plate with paraxial mesoderm or nonneural ectoderm can generate neural crest. Several signaling pathways converge at the border between neural and nonneural ectoderm where the neural crest will form. Among the molecules identified in this process are members of the BMP, Wnt, FGF and Notch signaling pathways. The concerted action of these nals and their downstream targets will define the identity of the neural crest.

Item Type:Book Section
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Bronner-Fraser, Marianne0000-0003-4274-1862
Additional Information:© 2006 Landes Bioscience and Springer Science. We would like to thank Dr. Andrew K. Groves for helpful comments on this manuscript.
Series Name:Advances in Experimental Medicine and Biology
Issue or Number:589
Record Number:CaltechAUTHORS:20160303-102135757
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Usage Policy:No commercial reproduction, distribution, display or performance rights in this work are provided.
ID Code:65000
Deposited By: Ruth Sustaita
Deposited On:04 Mar 2016 21:47
Last Modified:03 Oct 2019 09:43

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