Patterson, Paul H. (1992) The emerging neuropoietic cytokine family: first CDF/LIF, CNTF and IL-6; next ONC, MGF, GCSF? Current Opinion in Neurobiology, 2 (1). pp. 94-97. ISSN 0959-4388. doi:10.1016/0959-4388(92)90169-L. https://resolver.caltech.edu/CaltechAUTHORS:20160309-075030291
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Abstract
CDF/LIF is a polyfunctional cytokine that shares a remarkable overlap with ciliary neurotrophic factor in its actions on neurons, and with interleukin-6 in its actions on other tissues. Moreover, the receptors for this cytokine, as well as those for ciliary neurotrophic factor, share homology with the subunits of the interleukin-6 receptor. The predicted structural similarity of these proteins with oncostatin M, myelomonocytic growth factor and granulocyte colony-stimulating factor, as well as at least a partial overlap in biological activities, is now prompting further examination of their roles in neuronal gene expression.
Item Type: | Article | |||||||||
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Additional Information: | © 1992 Current Biology Ltd. | |||||||||
Issue or Number: | 1 | |||||||||
DOI: | 10.1016/0959-4388(92)90169-L | |||||||||
Record Number: | CaltechAUTHORS:20160309-075030291 | |||||||||
Persistent URL: | https://resolver.caltech.edu/CaltechAUTHORS:20160309-075030291 | |||||||||
Official Citation: | Paul H. Patterson, The emerging neuropoietic cytokine family: first CDF/LIF, CNTF and IL-6; next ONC, MGF, GCSF?, Current Opinion in Neurobiology, Volume 2, Issue 1, February 1992, Pages 94-97, ISSN 0959-4388, http://dx.doi.org/10.1016/0959-4388(92)90169-L. (http://www.sciencedirect.com/science/article/pii/095943889290169L) | |||||||||
Usage Policy: | No commercial reproduction, distribution, display or performance rights in this work are provided. | |||||||||
ID Code: | 65227 | |||||||||
Collection: | CaltechAUTHORS | |||||||||
Deposited By: | Ruth Sustaita | |||||||||
Deposited On: | 09 Mar 2016 18:27 | |||||||||
Last Modified: | 10 Nov 2021 23:41 |
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