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The emerging neuropoietic cytokine family: first CDF/LIF, CNTF and IL-6; next ONC, MGF, GCSF?

Patterson, Paul H. (1992) The emerging neuropoietic cytokine family: first CDF/LIF, CNTF and IL-6; next ONC, MGF, GCSF? Current Opinion in Neurobiology, 2 (1). pp. 94-97. ISSN 0959-4388. doi:10.1016/0959-4388(92)90169-L. https://resolver.caltech.edu/CaltechAUTHORS:20160309-075030291

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Abstract

CDF/LIF is a polyfunctional cytokine that shares a remarkable overlap with ciliary neurotrophic factor in its actions on neurons, and with interleukin-6 in its actions on other tissues. Moreover, the receptors for this cytokine, as well as those for ciliary neurotrophic factor, share homology with the subunits of the interleukin-6 receptor. The predicted structural similarity of these proteins with oncostatin M, myelomonocytic growth factor and granulocyte colony-stimulating factor, as well as at least a partial overlap in biological activities, is now prompting further examination of their roles in neuronal gene expression.


Item Type:Article
Related URLs:
URLURL TypeDescription
http://dx.doi.org/10.1016/0959-4388(92)90169-LDOIArticle
http://www.sciencedirect.com/science/article/pii/095943889290169LPublisherArticle
Additional Information:© 1992 Current Biology Ltd.
Issue or Number:1
DOI:10.1016/0959-4388(92)90169-L
Record Number:CaltechAUTHORS:20160309-075030291
Persistent URL:https://resolver.caltech.edu/CaltechAUTHORS:20160309-075030291
Official Citation:Paul H. Patterson, The emerging neuropoietic cytokine family: first CDF/LIF, CNTF and IL-6; next ONC, MGF, GCSF?, Current Opinion in Neurobiology, Volume 2, Issue 1, February 1992, Pages 94-97, ISSN 0959-4388, http://dx.doi.org/10.1016/0959-4388(92)90169-L. (http://www.sciencedirect.com/science/article/pii/095943889290169L)
Usage Policy:No commercial reproduction, distribution, display or performance rights in this work are provided.
ID Code:65227
Collection:CaltechAUTHORS
Deposited By: Ruth Sustaita
Deposited On:09 Mar 2016 18:27
Last Modified:10 Nov 2021 23:41

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