A Caltech Library Service

Manipulations of Neural Crest Cells or Their Migratory Pathways

Bronner-Fraser, Marianne (1996) Manipulations of Neural Crest Cells or Their Migratory Pathways. In: Methods in Avian Embryology. Methods in Cell Biology . Vol.51. No.51. Academic Press , San Diego, CA, pp. 61-79. ISBN 9780125641531.

Full text is not posted in this repository. Consult Related URLs below.

Use this Persistent URL to link to this item:


This chapter discusses the manipulations of neural crest cells or their migratory pathways. The formation of the embryo involves intricate cell movements, cell proliferation, and differentiation. The neural crest has long served as a model for the study of these processes, because neural crest cells undergo extensive migrations and give rise to many diverse derivatives. Neural crest cells arise from the dorsal portion of the neural tube. Several unique properties of these cells make the neural crest an ideal system for studying cell migration and differentiation. First, these cells migrate extensively along characteristic pathways. Second, they give rise to diverse and numerous derivatives, ranging from pigment cells and cranial cartilage to adrenal chromaffin cells and the ganglia of the peripheral nervous system. In addition, their characteristic position of premigratory neural crest cells within the dorsal portion of the neural tube makes them accessible to surgical and molecular manipulations during the initial stages in their development.

Item Type:Book Section
Related URLs:
URLURL TypeDescription
Bronner-Fraser, Marianne0000-0003-4274-1862
Additional Information:© 1996 Academic Press, Inc. The author thanks Drs. Mary Dickinson, Scott Fraser, and Catherine Krull for helpful comments on the manuscript. Development of some of the methods described in this chapter comes from support by NIH Grants HD-25138, HD-15527, and DE-10066.
Funding AgencyGrant Number
Series Name:Methods in Cell Biology
Issue or Number:51
Record Number:CaltechAUTHORS:20160310-141731239
Persistent URL:
Official Citation:Marianne Bronner-Fraser, Chapter 3 Manipulations of Neural Crest Cells or Their Migratory Pathways, In: Marianne Bronner-Fraser, Editor(s), Methods in Cell Biology, Academic Press, 1996, Volume 51, Pages 61-79, ISSN 0091-679X, ISBN 9780125641531, (
Usage Policy:No commercial reproduction, distribution, display or performance rights in this work are provided.
ID Code:65267
Deposited By: Ruth Sustaita
Deposited On:10 Mar 2016 22:28
Last Modified:10 Nov 2021 23:42

Repository Staff Only: item control page