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Pattern formation and developmental mechanisms. Converging views of diverging pathways

Kim, Stuart K. and Fraser, Scott E. (1998) Pattern formation and developmental mechanisms. Converging views of diverging pathways. Current Opinion in Genetics and Development, 8 (4). pp. 383-385. ISSN 0959-437X. doi:10.1016/S0959-437X(98)80106-8.

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One of the great themes in modern developmental biology is the underlying unity of developmental mechanisms that govern pattern formation in all animals. Superficially, many classical paradigms of developmental patterning appear to be quite different. In the last decade, these classical experimental systems have been found to be based upon similar signaling pathways and regulatory hierarchies. For example, anterior/posterior patterning in all animals are governed by the genes in the Hox cluster(s), and axis formation in the frog egg, limb development and pattern formation in insect wings are established by common signaling pathways. There has been great joy in discovering the unity in mechanisms for developmental patterning and there is also great power in knowing that similar types of genetic pathways regulate patterning in all animals.

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Fraser, Scott E.0000-0002-5377-0223
Additional Information:© 1998 Current Biology Publications.
Issue or Number:4
Record Number:CaltechAUTHORS:20160311-065129390
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Official Citation:Stuart K Kim, Scott E Fraser, Pattern formation and developmental mechanisms Converging views of diverging pathways, Current Opinion in Genetics & Development, Volume 8, Issue 4, August 1998, Pages 383-385, ISSN 0959-437X, (
Usage Policy:No commercial reproduction, distribution, display or performance rights in this work are provided.
ID Code:65286
Deposited By: Ruth Sustaita
Deposited On:14 Mar 2016 20:36
Last Modified:10 Nov 2021 23:42

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