A Caltech Library Service

Differentiation of the vertebrate neural tube

Bronner-Fraser, Marianne and Fraser, Scott E. (1997) Differentiation of the vertebrate neural tube. Current Opinion in Cell Biology, 9 (6). pp. 885-891. ISSN 0955-0674. doi:10.1016/S0955-0674(97)80092-0.

Full text is not posted in this repository. Consult Related URLs below.

Use this Persistent URL to link to this item:


The vertebrate nervous system arises through a series of inductive interactions, beginning with the induction of the neural plate and the rostrocaudal patterning of the neural tube. The process continues with dorsoventral patterning of the neural tube, during which floor plate cells and motor neurons are induced ventrally by interactions of the neural tube with the notochord, and dorsal cell types are induced via neural plate/ectodermal interactions. Later interactions result in the formation of interneurons as well as neuronal migrations. Recent progress, guided in part by knowledge of evolutionary conservation of transcription factors and signaling pathways, is beginning to reveal the cellular and molecular bases of each of these steps in neuronal patterning.

Item Type:Article
Related URLs:
URLURL TypeDescription
Bronner-Fraser, Marianne0000-0003-4274-1862
Fraser, Scott E.0000-0002-5377-0223
Additional Information:© 1997 Current Biology Ltd. Available online 4 July 2002. We thank Andrew Groves and Anne Knecht for helpful comments on the manuscript.
Issue or Number:6
Record Number:CaltechAUTHORS:20160323-142240057
Persistent URL:
Official Citation:Marianne Bronner-Fraser, Scott E Fraser, Differentiation of the vertebrate neural tube, Current Opinion in Cell Biology, Volume 9, Issue 6, December 1997, Pages 885-891, ISSN 0955-0674, (
Usage Policy:No commercial reproduction, distribution, display or performance rights in this work are provided.
ID Code:65633
Deposited By: Ruth Sustaita
Deposited On:24 Mar 2016 16:17
Last Modified:10 Nov 2021 23:48

Repository Staff Only: item control page