Lemke, R. and Gadient, R. A. and Patterson, P. H. and Bigl, V. and Schliebs, R. (1997) Leukemia inhibitory factor (LIF) mRNA-expressing neuronal subpopulations in adult rat basal forebrain. Neuroscience Letters, 229 (1). pp. 69-71. ISSN 0304-3940. doi:10.1016/S0304-3940(97)00421-7. https://resolver.caltech.edu/CaltechAUTHORS:20160411-131735028
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Abstract
We have previously found leukemia inhibitory factor (LIF) mRNA in neurons of the adult rat brain. To identify which neuronal subpopulations are expressing LIF transcripts, non-radioactive in situ hybridization was combined with immunocytochemistry for various neuronal markers. Studying the rat basal forebrain and cerebral cortex, we find LIF mRNA is expressed in both cholinergic and GABAergic neurons. These data suggest a role for LIF in the function of these mature neurons.
Item Type: | Article | ||||||||||||
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Additional Information: | © 1997 Elsevier Science Ireland Ltd. Received 2 April 1997; received in revised form 2 June 1997; accepted 2 June 1997. Available online 23 July 1997. This work was supported by the University of Leipzig Medical Faculty, grant no. 762116 to R.S. and by a grant from the NIH to P.H.P. R.L. is a recipient of a stipend from the Studienstiftung des Deutschen Volkes e.V., and R.A.G. is supported by the Swiss National Science Foundation and the Roche Research Foundation. | ||||||||||||
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Subject Keywords: | Cholinergic differentiation factor; Glial fibrillary acidic protein; Choline acetyltransferase; Parvalbumin; Calretinin | ||||||||||||
Issue or Number: | 1 | ||||||||||||
DOI: | 10.1016/S0304-3940(97)00421-7 | ||||||||||||
Record Number: | CaltechAUTHORS:20160411-131735028 | ||||||||||||
Persistent URL: | https://resolver.caltech.edu/CaltechAUTHORS:20160411-131735028 | ||||||||||||
Official Citation: | R Lemke, R.A Gadient, P.H Patterson, V Bigl, R Schliebs, Leukemia inhibitory factor (LIF) mRNA-expressing neuronal subpopulations in adult rat basal forebrain, Neuroscience Letters, Volume 229, Issue 1, 20 June 1997, Pages 69-71, ISSN 0304-3940, http://dx.doi.org/10.1016/S0304-3940(97)00421-7. (http://www.sciencedirect.com/science/article/pii/S0304394097004217) | ||||||||||||
Usage Policy: | No commercial reproduction, distribution, display or performance rights in this work are provided. | ||||||||||||
ID Code: | 66054 | ||||||||||||
Collection: | CaltechAUTHORS | ||||||||||||
Deposited By: | Ruth Sustaita | ||||||||||||
Deposited On: | 11 Apr 2016 20:35 | ||||||||||||
Last Modified: | 10 Nov 2021 23:52 |
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