Ponce, Maria R. and Micol, José L. and Peterson, Kevin J. and Davidson, Eric H. (1999) Molecular Characterization and Phylogenetic Analysis of SpBMP5–7, a New Member of the TGF-β Superfamily Expressed in Sea Urchin Embryos. Molecular Biology and Evolution, 16 (5). pp. 634-645. ISSN 0737-4038. https://resolver.caltech.edu/CaltechAUTHORS:20160411-144512549
Full text is not posted in this repository. Consult Related URLs below.
Use this Persistent URL to link to this item: https://resolver.caltech.edu/CaltechAUTHORS:20160411-144512549
Abstract
TGF-β ligands are probably pan-bilaterian in phylogenetic distribution. The family appears to have diversified greatly with the evolution of the vertebrates, but only a few invertebrate deuterostome TGF-β molecules have so far been isolated. A search for members of this family expressed in sea urchin embryos, using canonical PCR primers, revealed a single-copy gene encoding a new TGF-β protein. The sequence which it encodes is closely related to those of vertebrate bone morphogenetic proteins (BMPs) 5-7. No additional TGF-β family members were uncovered other than univin, which had previously been reported.
| Item Type: | Article | ||||||
|---|---|---|---|---|---|---|---|
| Related URLs: |
| ||||||
| Additional Information: | © 1999 Society for Molecular Biology and Evolution. Accepted January 18, 1999. Stephen Palumbi, reviewing editor. This work was supported by NIH grant HD-05753 and NATO CRG 931023. M.R.P. was a fellow of Fundaciόn Rich. We are indebted to Markus Friedrich for assistance with the phylogenetic analyses and to R. Andrew Cameron for his careful review of a draft of this manuscript. | ||||||
| Funders: |
| ||||||
| Subject Keywords: | TGF-β superfamily, bone morphogenetic proteins, sea urchin embryogenesis | ||||||
| Issue or Number: | 5 | ||||||
| Record Number: | CaltechAUTHORS:20160411-144512549 | ||||||
| Persistent URL: | https://resolver.caltech.edu/CaltechAUTHORS:20160411-144512549 | ||||||
| Official Citation: | M R Ponce, J L Micol, K J Peterson, and E H Davidson Molecular characterization and phylogenetic analysis of SpBMP5-7, a new member of the TGF-beta superfamily expressed in sea urchin embryos. Mol Biol Evol (1999) 16 (5): 634-645 | ||||||
| Usage Policy: | No commercial reproduction, distribution, display or performance rights in this work are provided. | ||||||
| ID Code: | 66056 | ||||||
| Collection: | CaltechAUTHORS | ||||||
| Deposited By: | Ruth Sustaita | ||||||
| Deposited On: | 12 Apr 2016 23:06 | ||||||
| Last Modified: | 03 Oct 2019 09:53 |
Repository Staff Only: item control page
