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Complete Sequence of SpHox8 and Its Linkage in the Single Hox Gene Cluster of Strongylocentrotus purpuratus

Martinez, Pedro and Lee, Jason C.-M. and Davidson, Eric H. (1997) Complete Sequence of SpHox8 and Its Linkage in the Single Hox Gene Cluster of Strongylocentrotus purpuratus. Journal of Molecular Evolution, 44 (4). pp. 371-377. ISSN 0022-2844. doi:10.1007/PL00006156.

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SpHox8 is the paralog group 8 Hox gene of Strongylocentrotus purpuratus. This identification follows from an analysis of the sequence of the complete open reading frame of a late-gastrula-stage cDNA clone; from direct linkage to adjacent Hox genes in a fosmid contig; and from blot hybridizations carried out on pulse field gel electrophoretic separations. SpHox8 is a single-copy gene, and there is only one Hox gene cluster per genome in S. purpuratus.

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Additional Information:© 1997 Springer-Verlag New York Inc. Received: 7 November 1996. Accepted: 4 December 1996. It is a pleasure to acknowledge the assistance of Dr. Tom Wilkie in the design of oligonucleotides and of Valeria Mancino with pulse field gel electrophoesis. We are grateful to Drs. Kevin Peterson and Roy Britten of this Institute for reviews of drafts of the manuscript. This work was supported by NICHHD grant 05753 and by the Stowers Institute for Medical Research.
Funding AgencyGrant Number
National Institute of Child Health and Human Development (NICHD)05753
Stowers Institute for Medical ResearchUNSPECIFIED
Subject Keywords:SpHox8, Strongylocentrotus purpuratus, Hox gene cluster
Issue or Number:4
Record Number:CaltechAUTHORS:20160412-105153369
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Usage Policy:No commercial reproduction, distribution, display or performance rights in this work are provided.
ID Code:66086
Deposited By: Ruth Sustaita
Deposited On:12 Apr 2016 21:31
Last Modified:10 Nov 2021 23:53

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