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Developmental Expression of Two Cloned Sequences Coding for Rare Sea Urchin Embryo Messages

Lev, Ze'ev and Thomas, Terry L. and Lee, Amy S. and Angerer, Robert C. and Britten, Roy J. and Davidson, Eric H. (1980) Developmental Expression of Two Cloned Sequences Coding for Rare Sea Urchin Embryo Messages. Developmental Biology, 76 (2). pp. 322-340. ISSN 0012-1606. doi:10.1016/0012-1606(80)90382-6. https://resolver.caltech.edu/CaltechAUTHORS:20160413-091052613

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Abstract

Measurements are presented of the number of transcripts in sea urchin embryos and in adult intestine cells complementary to two cloned genomic single copy sequences. These sequences apparently code for maternal mRNAs stored in the egg. About 1000 and 1400 transcripts are stored per egg, close to the average value for maternal mRNAs. RNAs complementary to the cloned sequences are also found in the polysomal message of early embryos. The number of polysomal transcripts representing each cloned sequence is typical of the “complex” or “rare” class of message in sea urchin embryos. Expression of these putative complex class structural genes is regulated developmentally. Thus, polysomal transcripts of both sequences essentially disappear by the blastula stage. One sequence is again represented at a low level in adult intestine cytoplasmic RNA while the other is absent. However, in all the developmental stages examined, the number of nuclear transcripts of the cloned sequences remains about the same as for any average single copy sequence transcript.


Item Type:Article
Related URLs:
URLURL TypeDescription
http://dx.doi.org/10.1016/0012-1606(80)90382-6DOIArticle
http://www.sciencedirect.com/science/article/pii/0012160680903826PublisherArticle
Additional Information:© 1980 Academic Press, Inc. Received October 9, 1979; accepted October 31, 1979. A This research was supported by a grant from the National Institute of Child Health and Human Development. Z.L. was supported by a Chaim Weizmann Fellowship; T.L.T. by an NIH Fellowship and a Lievre Fellowship from the American Cancer Society, California Division; A.S.L. by an NIH Fellowship and a Senior Fellowship from the American Cancer Society, California Division; and R.C.A. by a Fellowship from the American Cancer Society and by the National Foundation-March of Dimes.
Funders:
Funding AgencyGrant Number
National Institute of Child Health and Human Development (NICHD)UNSPECIFIED
Chaim Weizmann FellowshipUNSPECIFIED
NIH Postdoctoral FellowshipUNSPECIFIED
American Cancer Society, California DivisionUNSPECIFIED
National Foundation - March of DimesUNSPECIFIED
Issue or Number:2
DOI:10.1016/0012-1606(80)90382-6
Record Number:CaltechAUTHORS:20160413-091052613
Persistent URL:https://resolver.caltech.edu/CaltechAUTHORS:20160413-091052613
Official Citation:Ze'ev Lev, Terry L. Thomas, Amy S. Lee, Robert C. Angerer, Roy J. Britten, Eric H. Davidson, Developmental expression of two cloned sequences coding for rare sea urchin embryo messages, Developmental Biology, Volume 76, Issue 2, 1980, Pages 322-340, ISSN 0012-1606, http://dx.doi.org/10.1016/0012-1606(80)90382-6. (http://www.sciencedirect.com/science/article/pii/0012160680903826)
Usage Policy:No commercial reproduction, distribution, display or performance rights in this work are provided.
ID Code:66103
Collection:CaltechAUTHORS
Deposited By: Ruth Sustaita
Deposited On:13 Apr 2016 17:19
Last Modified:10 Nov 2021 23:53

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