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Optical phase conjugation assisted scattering lens: variable focusing and 3D patterning

Ryu, Jihee and Jang, Mooseok and Eom, Tae Joong and Yang, Changhuei and Chung, Euiheon (2016) Optical phase conjugation assisted scattering lens: variable focusing and 3D patterning. Scientific Reports, 6 . Art. No. 23494. ISSN 2045-2322. PMCID PMC4877672.

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Variable light focusing is the ability to flexibly select the focal distance of a lens. This feature presents technical challenges, but is significant for optical interrogation of three-dimensional objects. Numerous lens designs have been proposed to provide flexible light focusing, including zoom, fluid, and liquid-crystal lenses. Although these lenses are useful for macroscale applications, they have limited utility in micron-scale applications due to restricted modulation range and exacting requirements for fabrication and control. Here, we present a holographic focusing method that enables variable light focusing without any physical modification to the lens element. In this method, a scattering layer couples low-angle (transverse wave vector) components into a full angular spectrum, and a digital optical phase conjugation (DOPC) system characterizes and plays back the wavefront that focuses through the scattering layer. We demonstrate micron-scale light focusing and patterning over a wide range of focal distances of 22–51 mm. The interferometric nature of the focusing scheme also enables an aberration-free scattering lens. The proposed method provides a unique variable focusing capability for imaging thick specimens or selective photoactivation of neuronal networks.

Item Type:Article
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URLURL TypeDescription CentralArticle
Yang, Changhuei0000-0001-8791-0354
Additional Information:© 2016 Macmillan Publishers Limited. This work is licensed under a Creative Commons Attribution-NonCommercial-ShareALike 4.0 International License. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in the credit line; if the material is not included under the Creative Commons license, users will need to obtain permission from the license holder to reproduce the material. To view a copy of this license, visit received: 28 October 2015; accepted: 08 March 2016; Published: 06 April 2016. We thank Kiri Lee for helpful discussions. This research was supported by the GIST-Caltech Research Collaboration Project through a grant provided by GIST in 2015, the Institute of Medical System Engineering (iMSE) in the GIST, the Bio & Medical Technology Development Program of the National Research Foundation of Korea (2011-0019633), the New Growth Power Equipment Competitiveness Reinforcement Program (10047580), the Industrial Strategic Technology Development Program (10047943) of the Ministry of Trade, Industry & Energy of Korea, the National Institutes of Health (1DP2OD007307-01), and the National Institutes of Health BRAIN Initiative (1U01NS090577-01). Jihee Ryu & Mooseok Jang: These authors contributed equally to this work. Author Contributions: J.R. and M.J. contributed equally to the work. M.J. conceived the experiments. J.R. carried out the experiments. J.R. and M.J. analysed the data. All authors contributed to writing the manuscript. T.J.E., C.Y. and E.C. supervised the project. The authors declare no competing financial interests.
Funding AgencyGrant Number
GIST-Caltech Collaborative Research FundUNSPECIFIED
Institute of Medical System EngineeringUNSPECIFIED
National Research Foundation of Korea2011-0019633
Ministry of Trade, Industry and Energy (Korea)10047580
Ministry of Trade, Industry and Energy (Korea)10047943
PubMed Central ID:PMC4877672
Record Number:CaltechAUTHORS:20160429-135633578
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Official Citation:Ryu, J. et al. Optical phase conjugation assisted scattering lens: variable focusing and 3D patterning. Sci. Rep. 6, 23494; doi: 10.1038/srep23494 (2016).
Usage Policy:No commercial reproduction, distribution, display or performance rights in this work are provided.
ID Code:66555
Deposited By: Tony Diaz
Deposited On:02 May 2016 00:24
Last Modified:09 Mar 2020 13:19

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