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Addressing single molecules on DNA nanostructures

Cohen, Justin D. and Sadowski, John P. and Dervan, Peter B. (2007) Addressing single molecules on DNA nanostructures. Angewandte Chemie International Edition, 46 (42). pp. 7956-1959. ISSN 1433-7851. https://resolver.caltech.edu/CaltechAUTHORS:20160509-104246356

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Abstract

The synthesis of devices and materials from molecular components is a major goal of nanotechnology. Although many such molecular components have been demonstrated previously,1–3 the ability to combine these components into designed architectures containing significant complexity remains a challenge. By using the hybridization properties of DNA and Watson–Crick base pairing, it has been possible to create well-defined DNA architectures of increasing complexity.4 The structure of an assembled DNA complex is directly and uniquely determined by the sequence of the DNA bases, which can be designed and manipulated. These methods provide a versatile and programmable way to control the structure and architecture of DNA nanostructures.


Item Type:Article
Related URLs:
URLURL TypeDescription
http://dx.doi.org/10.1002/anie.200702767DOIArticle
http://onlinelibrary.wiley.com/doi/10.1002/anie.200702767/abstractPublisherArticle
http://www.wiley-vch.de/contents/jc_2002/2007/z702767_s.pdfPublisherSupporting Information
ORCID:
AuthorORCID
Dervan, Peter B.0000-0001-8852-7306
Additional Information:© 2007 Wiley-VCH Verlag GmbH & Co. Received: June 22, 2007. We are grateful for support from the Ralph M. Parsons Foundation and W. Webster. We thank Prof. Erik Winfree and Dr. Sung Ha Park for guidance on the AFM experiments and helpful discussions.
Funders:
Funding AgencyGrant Number
Ralph M. Parsons FoundationUNSPECIFIED
W. WebsterUNSPECIFIED
Subject Keywords:DNA, nanostructures, polyamides, self-assembly
Issue or Number:42
Record Number:CaltechAUTHORS:20160509-104246356
Persistent URL:https://resolver.caltech.edu/CaltechAUTHORS:20160509-104246356
Official Citation:Cohen, Justin D., Sadowski, John P. and Dervan, Peter B. (2007), Addressing Single Molecules on DNA Nanostructures. Angewandte Chemie International Edition, 46: 7956–7959. doi:10.1002/anie.200702767
Usage Policy:No commercial reproduction, distribution, display or performance rights in this work are provided.
ID Code:66743
Collection:CaltechAUTHORS
Deposited By: Victoria Brennan
Deposited On:17 May 2016 20:15
Last Modified:26 Nov 2019 11:15

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