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Recognition of the DNA minor groove by pyrrole-imidazole polyamides

Dervan, Peter B. and Edelson, Benjamin S. (2003) Recognition of the DNA minor groove by pyrrole-imidazole polyamides. Current Opinion in Structural Biology, 13 (3). pp. 284-299. ISSN 0959-440X. doi:10.1016/S0959-440X(03)00081-2. https://resolver.caltech.edu/CaltechAUTHORS:20160510-080150918

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Abstract

Many diseases, such as cancer, are related to aberrant gene expression. Regulating transcription by chemical methods could be important in human medicine. Minor groove-binding polyamides offer one chemical approach to DNA recognition.


Item Type:Article
Related URLs:
URLURL TypeDescription
http://dx.doi.org/10.1016/S0959-440X(03)00081-2DOIArticle
http://www.sciencedirect.com/science/article/pii/S0959440X03000812PublisherArticle
ORCID:
AuthorORCID
Dervan, Peter B.0000-0001-8852-7306
Additional Information:© 2003 Elsevier. Available online 11 June 2003. The work described in this review was supported by the National Institutes of Health. BSE is supported by a predoctoral fellowship from the Howard Hughes Medical Institute.
Funders:
Funding AgencyGrant Number
NIHUNSPECIFIED
Howard Hughes Medical Institute (HHMI)UNSPECIFIED
Issue or Number:3
DOI:10.1016/S0959-440X(03)00081-2
Record Number:CaltechAUTHORS:20160510-080150918
Persistent URL:https://resolver.caltech.edu/CaltechAUTHORS:20160510-080150918
Official Citation:Peter B Dervan, Benjamin S Edelson, Recognition of the DNA minor groove by pyrrole-imidazole polyamides, Current Opinion in Structural Biology, Volume 13, Issue 3, June 2003, Pages 284-299, ISSN 0959-440X, http://dx.doi.org/10.1016/S0959-440X(03)00081-2. (http://www.sciencedirect.com/science/article/pii/S0959440X03000812)
Usage Policy:No commercial reproduction, distribution, display or performance rights in this work are provided.
ID Code:66800
Collection:CaltechAUTHORS
Deposited By: Victoria Brennan
Deposited On:17 May 2016 22:43
Last Modified:11 Nov 2021 00:03

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