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Recognition of the DNA minor groove by pyrrole-imidazole polyamides

Dervan, Peter B. and Edelson, Benjamin S. (2003) Recognition of the DNA minor groove by pyrrole-imidazole polyamides. Current Opinion in Structural Biology, 13 (3). pp. 284-299. ISSN 0959-440X. doi:10.1016/S0959-440X(03)00081-2.

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Many diseases, such as cancer, are related to aberrant gene expression. Regulating transcription by chemical methods could be important in human medicine. Minor groove-binding polyamides offer one chemical approach to DNA recognition.

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Dervan, Peter B.0000-0001-8852-7306
Additional Information:© 2003 Elsevier. Available online 11 June 2003. The work described in this review was supported by the National Institutes of Health. BSE is supported by a predoctoral fellowship from the Howard Hughes Medical Institute.
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Howard Hughes Medical Institute (HHMI)UNSPECIFIED
Issue or Number:3
Record Number:CaltechAUTHORS:20160510-080150918
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Official Citation:Peter B Dervan, Benjamin S Edelson, Recognition of the DNA minor groove by pyrrole-imidazole polyamides, Current Opinion in Structural Biology, Volume 13, Issue 3, June 2003, Pages 284-299, ISSN 0959-440X, (
Usage Policy:No commercial reproduction, distribution, display or performance rights in this work are provided.
ID Code:66800
Deposited By: Victoria Brennan
Deposited On:17 May 2016 22:43
Last Modified:11 Nov 2021 00:03

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