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A synthetic peptide binds 16 base pairs of A,T double helical DNA

Youngquist, R. Scott and Dervan, Peter B. (1987) A synthetic peptide binds 16 base pairs of A,T double helical DNA. Journal of the American Chemical Society, 109 (24). pp. 7564-7566. ISSN 0002-7863. https://resolver.caltech.edu/CaltechAUTHORS:20160511-144024026

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Abstract

One approach to the design of synthetic sequence specific DNA binding molecules that bind large sequences of double helical DNA is to couple together DNA binding domains of similar or diverse base pairs specificities. The DNA binding domains should be linked together in a way that allows simultaneous binding of the units to contiguous DNA sequences.


Item Type:Article
Related URLs:
URLURL TypeDescription
http://dx.doi.org/10.1021/ja00258a070DOIArticle
http://pubs.acs.org/doi/abs/10.1021/ja00258a070PublisherArticle
ORCID:
AuthorORCID
Dervan, Peter B.0000-0001-8852-7306
Additional Information:© 1987 American Chemical Society. Received August 3, 1987. We are grateful to the National Institutes of Health for research support (GM-27681).
Funders:
Funding AgencyGrant Number
NIHGM-27681
Issue or Number:24
Record Number:CaltechAUTHORS:20160511-144024026
Persistent URL:https://resolver.caltech.edu/CaltechAUTHORS:20160511-144024026
Official Citation:A synthetic peptide binds 16 base pairs of A,T double helical DNA R. Scott Youngquist and Peter B. Dervan Journal of the American Chemical Society 1987 109 (24), 7564-7566 DOI: 10.1021/ja00258a070
Usage Policy:No commercial reproduction, distribution, display or performance rights in this work are provided.
ID Code:67008
Collection:CaltechAUTHORS
Deposited By: Victoria Brennan
Deposited On:19 May 2016 19:34
Last Modified:26 Nov 2019 11:15

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