Griffin, John H. and Dervan, Peter B. (1987) Metalloregulation in the sequence specific binding of synthetic molecules to DNA. Journal of the American Chemical Society, 109 (22). pp. 6840-6842. ISSN 0002-7863. doi:10.1021/ja00256a043. https://resolver.caltech.edu/CaltechAUTHORS:20160511-144439605
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Abstract
Specific metal cations exert remarkable effects on the transcription of several prokaryotic and eukaryotic genes. Recently, the DNA-binding eukaryotic transcription factor TFIIIA has been characterized as a series of peptide fingers connected by zinc-binding domains. These observations raise the issue of whether the binding of synthetic molecules to DNA could in some way be regulated by the addition of specific metal ions.
| Item Type: | Article | |||||||||
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| Additional Information: | © 1987 American Chemical Society. Received April 10, 1987. We are grateful to the National Institutes of Health for research support (GM 27681} and to the National Science Foundation for a predoctoral fellowship to J.H.G. | |||||||||
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| Issue or Number: | 22 | |||||||||
| DOI: | 10.1021/ja00256a043 | |||||||||
| Record Number: | CaltechAUTHORS:20160511-144439605 | |||||||||
| Persistent URL: | https://resolver.caltech.edu/CaltechAUTHORS:20160511-144439605 | |||||||||
| Official Citation: | Metalloregulation in the sequence specific binding of synthetic molecules to DNA John H. Griffin and Peter B. Dervan Journal of the American Chemical Society 1987 109 (22), 6840-6842 DOI: 10.1021/ja00256a043 | |||||||||
| Usage Policy: | No commercial reproduction, distribution, display or performance rights in this work are provided. | |||||||||
| ID Code: | 67010 | |||||||||
| Collection: | CaltechAUTHORS | |||||||||
| Deposited By: | Victoria Brennan | |||||||||
| Deposited On: | 19 May 2016 19:36 | |||||||||
| Last Modified: | 11 Nov 2021 00:25 |
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