Wade, Warren S. and Dervan, Peter B. (1987) Alteration of the sequence specificity of distamycin on DNA by replacement of an N-methylpyrrolecarboxamide with pyridine-2-carboxamide. Journal of the American Chemical Society, 109 (5). pp. 1574-1575. ISSN 0002-7863. doi:10.1021/ja00239a050. https://resolver.caltech.edu/CaltechAUTHORS:20160511-144847036
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Abstract
Although there has been some encouraging success with regard to building synthetic molecules that bind large sequences of pure A,T-rich double-helical DNA, there has not been corresponding success in the development of well-understood G,C recognition. Progress in this area is an important component in an overall strategy of coupling G,C words and A,T words into sentences that uniquely recognize long sequences of right-handed DNA.
| Item Type: | Article | |||||||||
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| Additional Information: | © 1987 American Chemical Society. Received September 8, 1986. We are grateful to the National Institutes of Health for research support (GM-27681) and to the National Science Foundation for a predoctoral fellowship to W.S.W. | |||||||||
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| Issue or Number: | 5 | |||||||||
| DOI: | 10.1021/ja00239a050 | |||||||||
| Record Number: | CaltechAUTHORS:20160511-144847036 | |||||||||
| Persistent URL: | https://resolver.caltech.edu/CaltechAUTHORS:20160511-144847036 | |||||||||
| Official Citation: | Alteration of the sequence specificity of distamycin on DNA by replacement of an N-methylpyrrolecarboxamide with pyridine-2-carboxamide Warren S. Wade and Peter B. Dervan Journal of the American Chemical Society 1987 109 (5), 1574-1575 DOI: 10.1021/ja00239a050 | |||||||||
| Usage Policy: | No commercial reproduction, distribution, display or performance rights in this work are provided. | |||||||||
| ID Code: | 67012 | |||||||||
| Collection: | CaltechAUTHORS | |||||||||
| Deposited By: | Victoria Brennan | |||||||||
| Deposited On: | 19 May 2016 19:39 | |||||||||
| Last Modified: | 11 Nov 2021 00:25 |
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