CaltechAUTHORS
  A Caltech Library Service

Alteration of the sequence specificity of distamycin on DNA by replacement of an N-methylpyrrolecarboxamide with pyridine-2-carboxamide

Wade, Warren S. and Dervan, Peter B. (1987) Alteration of the sequence specificity of distamycin on DNA by replacement of an N-methylpyrrolecarboxamide with pyridine-2-carboxamide. Journal of the American Chemical Society, 109 (5). pp. 1574-1575. ISSN 0002-7863. https://resolver.caltech.edu/CaltechAUTHORS:20160511-144847036

Full text is not posted in this repository. Consult Related URLs below.

Use this Persistent URL to link to this item: https://resolver.caltech.edu/CaltechAUTHORS:20160511-144847036

Abstract

Although there has been some encouraging success with regard to building synthetic molecules that bind large sequences of pure A,T-rich double-helical DNA, there has not been corresponding success in the development of well-understood G,C recognition. Progress in this area is an important component in an overall strategy of coupling G,C words and A,T words into sentences that uniquely recognize long sequences of right-handed DNA.


Item Type:Article
Related URLs:
URLURL TypeDescription
http://dx.doi.org/10.1021/ja00239a050DOIArticle
http://pubs.acs.org/doi/abs/10.1021/ja00239a050PublisherArticle
ORCID:
AuthorORCID
Dervan, Peter B.0000-0001-8852-7306
Additional Information:© 1987 American Chemical Society. Received September 8, 1986. We are grateful to the National Institutes of Health for research support (GM-27681) and to the National Science Foundation for a predoctoral fellowship to W.S.W.
Funders:
Funding AgencyGrant Number
NIHGM-27681
NSF Predoctoral FellowshipUNSPECIFIED
Issue or Number:5
Record Number:CaltechAUTHORS:20160511-144847036
Persistent URL:https://resolver.caltech.edu/CaltechAUTHORS:20160511-144847036
Official Citation:Alteration of the sequence specificity of distamycin on DNA by replacement of an N-methylpyrrolecarboxamide with pyridine-2-carboxamide Warren S. Wade and Peter B. Dervan Journal of the American Chemical Society 1987 109 (5), 1574-1575 DOI: 10.1021/ja00239a050
Usage Policy:No commercial reproduction, distribution, display or performance rights in this work are provided.
ID Code:67012
Collection:CaltechAUTHORS
Deposited By: Victoria Brennan
Deposited On:19 May 2016 19:39
Last Modified:26 Nov 2019 11:15

Repository Staff Only: item control page