Sinsheimer, Robert L. (1959) Is The Nucleic Acid Message in a Two-Symbol Code? Journal of Molecular Biology, 1 (3). pp. 218-220. ISSN 0022-2836. https://resolver.caltech.edu/CaltechAUTHORS:20160531-082128951
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Abstract
In order to account for the diversity of adenine : guanine ratios in the deoxyribonucleic acids (DNA) of various microorganisms, it is proposed that the code in DNA is a two-symbol code. Specifically, it is proposed that the code is a sequence of 6-amino or 6-keto groups and thus adenine is equivalent to cytosine and guanine to thymine (or, in RNA, to uracil). This hypothesis also provides a convenient explanation of the near-equivalence of 6-amino and 6-keto nucleotides in the total RNA of various organisms.
| Item Type: | Article | |||||||||
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| Additional Information: | © 1959 Elsevier Ltd. Received 27 April 1959. | |||||||||
| Issue or Number: | 3 | |||||||||
| Record Number: | CaltechAUTHORS:20160531-082128951 | |||||||||
| Persistent URL: | https://resolver.caltech.edu/CaltechAUTHORS:20160531-082128951 | |||||||||
| Official Citation: | Robert L. Sinsheimer, Is the nucleic acid message in a two-symbol code?, Journal of Molecular Biology, Volume 1, Issue 3, 1959, Pages 218-220, ISSN 0022-2836, http://dx.doi.org/10.1016/S0022-2836(59)80028-0. (http://www.sciencedirect.com/science/article/pii/S0022283659800280) | |||||||||
| Usage Policy: | No commercial reproduction, distribution, display or performance rights in this work are provided. | |||||||||
| ID Code: | 67475 | |||||||||
| Collection: | CaltechAUTHORS | |||||||||
| Deposited By: | Ruth Sustaita | |||||||||
| Deposited On: | 31 May 2016 23:36 | |||||||||
| Last Modified: | 03 Oct 2019 10:06 |
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