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The Action of Pancreatic Deoxyribonuclease. II. Isomeric Dinucleotides

Sinsheimer, Robert L. (1955) The Action of Pancreatic Deoxyribonuclease. II. Isomeric Dinucleotides. Journal of Biological Chemistry, 215 (1). pp. 579-583. ISSN 0021-9258.

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In Paper I (1) methods were described for the isolation of dideoxyribonucleotides from digests of deoxyribonucleic acid (DNA) by pancreatic deoxyribonuclease (DNase). Dinucleotides composed of unlike mononucleotides were obtained as mixtures of the two possible sequential isomers. Methods have now been developed for the analysis of the proportions of the isomers in such mixtures and applied to the dinucleotide fractions obtained by the action of DNase on DNA from calf thymus.

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Additional Information:© 1955 American Society for Biochemistry and Molecular Biology. Received for publication, November 15, 1954. The research described in this paper was supported by a grant from the United States Public Health Service.
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U.S. Public Health Service (USPHS)UNSPECIFIED
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Official Citation:THE ACTION OF PANCREATIC DEOXYRIBONUCLEASE: II. ISOMERIC DINUCLEOTIDES Robert L. Sinsheimer J. Biol. Chem. 1955 215: 579-583.
Usage Policy:No commercial reproduction, distribution, display or performance rights in this work are provided.
ID Code:67485
Deposited By: Ruth Sustaita
Deposited On:31 May 2016 23:30
Last Modified:03 Oct 2019 10:06

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