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The Replication of Bacteriophage MS2: VII. Non-conservative Replication of Double-stranded RNA

Kelly, Regis B. and Sinsheimer, Robert L. (1967) The Replication of Bacteriophage MS2: VII. Non-conservative Replication of Double-stranded RNA. Journal of Molecular Biology, 26 (2). pp. 169-179. ISSN 0022-2836. http://resolver.caltech.edu/CaltechAUTHORS:20160601-083027128

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Abstract

The replication of phage-specific RNA duplexes in cells infected with the bacteriophage MS2 has been studied by means of density labeling and CsCl equilibrium density sedimentation. It was found that the input parental RNA strand enters a duplex and that progeny duplexes appear soon afterwards, with approximately exponential kinetics. Chase experiments indicate that most of the parental and progeny duplexes are not conserved.


Item Type:Article
Related URLs:
URLURL TypeDescription
http://dx.doi.org/10.1016/0022-2836(67)90289-6DOIArticle
http://www.sciencedirect.com/science/article/pii/0022283667902896PublisherArticle
Additional Information:© 1967 Elsevier Ltd. Received 25 January 1967. This work was supported by grants RG6965 and GM13554 from the U.S. Public Health Service.
Funders:
Funding AgencyGrant Number
U.S. Public Health Service (USPHS)RG6965
U.S. Public Health Service (USPHS)GM13554
Record Number:CaltechAUTHORS:20160601-083027128
Persistent URL:http://resolver.caltech.edu/CaltechAUTHORS:20160601-083027128
Official Citation:Regis B. Kelly, Robert L. Sinsheimer, The replication of bacteriophage MS2, Journal of Molecular Biology, Volume 26, Issue 2, 1967, Pages 169-179, ISSN 0022-2836, http://dx.doi.org/10.1016/0022-2836(67)90289-6. (http://www.sciencedirect.com/science/article/pii/0022283667902896)
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ID Code:67518
Collection:CaltechAUTHORS
Deposited By: Ruth Sustaita
Deposited On:01 Jun 2016 21:09
Last Modified:01 Jun 2016 21:09

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