Bronner, Marianne E. (2016) How inhibitory cues can both constrain and promote cell migration. Journal of Cell Biology, 213 (5). pp. 505-507. ISSN 0021-9525. PMCID PMC4896061. http://resolver.caltech.edu/CaltechAUTHORS:20160610-133948679
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Abstract
Collective cell migration is a common feature in both embryogenesis and metastasis. By coupling studies of neural crest migration in vivo and in vitro with mathematical modeling, Szabó et al. (2016, J. Cell Biol., http://dx.doi.org/10.1083/jcb.201602083) demonstrate that the proteoglycan versican forms a physical boundary that constrains neural crest cells to discrete streams, in turn facilitating their migration.
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| Additional Information: | © 2016 Bronner. After the Initial Publication Period, RUP will grant to the public the non-exclusive right to copy, distribute, or display the Work under a Creative Commons Attribution-Noncommercial-Share Alike 3.0 Unpor ted license as described at http://creativecommons.org/licenses/by-nc-sa/3.0/ and http://creativecommons.org/licenses/by-nc-sa/3.0/legalcode. Submitted: 19 May 2016; Accepted: 20 May 2016. I thank Paige O’Connell for drawing Fig. 1. Work in the Bronner laboratory is supported by National Institutes of Health grants DE024157 and HD037105. The author declares no conflicting financial interests. | ||||||||||||
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| PubMed Central ID: | PMC4896061 | ||||||||||||
| Record Number: | CaltechAUTHORS:20160610-133948679 | ||||||||||||
| Persistent URL: | http://resolver.caltech.edu/CaltechAUTHORS:20160610-133948679 | ||||||||||||
| Official Citation: | How inhibitory cues can both constrain and promote cell migration Marianne E. Bronner J Cell Biol 2016 213:505-507. Published June 6, 2016, doi:10.1083/jcb.201605074 | ||||||||||||
| Usage Policy: | No commercial reproduction, distribution, display or performance rights in this work are provided. | ||||||||||||
| ID Code: | 67845 | ||||||||||||
| Collection: | CaltechAUTHORS | ||||||||||||
| Deposited By: | Tony Diaz | ||||||||||||
| Deposited On: | 10 Jun 2016 22:12 | ||||||||||||
| Last Modified: | 06 Dec 2016 23:07 |
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