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How inhibitory cues can both constrain and promote cell migration

Bronner, Marianne E. (2016) How inhibitory cues can both constrain and promote cell migration. Journal of Cell Biology, 213 (5). pp. 505-507. ISSN 0021-9525. PMCID PMC4896061. http://resolver.caltech.edu/CaltechAUTHORS:20160610-133948679

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Abstract

Collective cell migration is a common feature in both embryogenesis and metastasis. By coupling studies of neural crest migration in vivo and in vitro with mathematical modeling, Szabó et al. (2016, J. Cell Biol., http://dx.doi.org/10.1083/jcb.201602083) demonstrate that the proteoglycan versican forms a physical boundary that constrains neural crest cells to discrete streams, in turn facilitating their migration.


Item Type:Article
Related URLs:
URLURL TypeDescription
http://dx.doi.org/10.1083/jcb.201605074DOIArticle
http://jcb.rupress.org/content/213/5/505PublisherArticle
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4896061/PubMed CentralArticle
ORCID:
AuthorORCID
Bronner, Marianne E.0000-0003-4274-1862
Additional Information:© 2016 Bronner. After the Initial Publication Period, RUP will grant to the public the non-exclusive right to copy, distribute, or display the Work under a Creative Commons Attribution-Noncommercial-Share Alike 3.0 Unpor ted license as described at http://creativecommons.org/licenses/by-nc-sa/3.0/ and http://creativecommons.org/licenses/by-nc-sa/3.0/legalcode. Submitted: 19 May 2016; Accepted: 20 May 2016. I thank Paige O’Connell for drawing Fig. 1. Work in the Bronner laboratory is supported by National Institutes of Health grants DE024157 and HD037105. The author declares no conflicting financial interests.
Funders:
Funding AgencyGrant Number
NIHDE024157
NIHHD037105
PubMed Central ID:PMC4896061
Record Number:CaltechAUTHORS:20160610-133948679
Persistent URL:http://resolver.caltech.edu/CaltechAUTHORS:20160610-133948679
Official Citation:How inhibitory cues can both constrain and promote cell migration Marianne E. Bronner J Cell Biol 2016 213:505-507. Published June 6, 2016, doi:10.1083/jcb.201605074
Usage Policy:No commercial reproduction, distribution, display or performance rights in this work are provided.
ID Code:67845
Collection:CaltechAUTHORS
Deposited By: Tony Diaz
Deposited On:10 Jun 2016 22:12
Last Modified:06 Dec 2016 23:07

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