Birdwell, Charles R. and Strauss, Ellen G. and Strauss, James H. (1973) Replication of Sindbis Virus III. An Electron Microscopic Study of Virus Maturation Using the Surface Replica Technique. Virology, 56 (2). pp. 429-438. ISSN 0042-6822. doi:10.1016/0042-6822(73)90047-0. https://resolver.caltech.edu/CaltechAUTHORS:20160613-145752635
Full text is not posted in this repository. Consult Related URLs below.
Use this Persistent URL to link to this item: https://resolver.caltech.edu/CaltechAUTHORS:20160613-145752635
Abstract
We have examined surface replicas of chick embryo cells infected with Sindbis virus. In some cells the virus buds over extensive areas of the cell surface, although there are areas where budding virus is clustered and other regions almost devoid of budding figures . In other cells, virus budding occurs primarily or exclusively at the periphery of the monolayer cells. Budding in these cells often occurs in long processes extending from the cell, which have widths from one to several virion diameters and lengths up to 7μm. These processes have also been examined by means of thin sections to visualize their internal features, especially the presence of nucleocapsids in the process of budding.
| Item Type: | Article | ||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|
| Related URLs: |
| ||||||||||
| Additional Information: | © 1973 Elsevier Inc. Accepted August 28, 1973. We are grateful to Dr. Jean-Paul Revel for pointing out the advantages of the surface-replica technique to us and for providing instruction and encouragement throughout the course of this project. We are also indebted to Dr. Ross Johnson for suggesting the thin-section experiments and to Mr . Pat Koen for assistance in cutting sections. Edith Lenches and Shaman Christoph provided excellent technical assistance. This research was supported by Grants GM 06905 and AI 10793 from the U.S. Public Health Service and by Grant GB 31763X from the National Science Foundation. One of us (C. R. B.) was supported by U.S. Public Health Service Training Grant GM-86. | ||||||||||
| Funders: |
| ||||||||||
| Issue or Number: | 2 | ||||||||||
| DOI: | 10.1016/0042-6822(73)90047-0 | ||||||||||
| Record Number: | CaltechAUTHORS:20160613-145752635 | ||||||||||
| Persistent URL: | https://resolver.caltech.edu/CaltechAUTHORS:20160613-145752635 | ||||||||||
| Official Citation: | Charles R. Birdwell, Ellen G. Strauss, James H. Strauss, Replication of Sindbis virus, Virology, Volume 56, Issue 2, 1973, Pages 429-438, ISSN 0042-6822, http://dx.doi.org/10.1016/0042-6822(73)90047-0. (http://www.sciencedirect.com/science/article/pii/0042682273900470) | ||||||||||
| Usage Policy: | No commercial reproduction, distribution, display or performance rights in this work are provided. | ||||||||||
| ID Code: | 67890 | ||||||||||
| Collection: | CaltechAUTHORS | ||||||||||
| Deposited By: | Donna Wrublewski | ||||||||||
| Deposited On: | 13 Jun 2016 23:59 | ||||||||||
| Last Modified: | 11 Nov 2021 03:56 |
Repository Staff Only: item control page
