Continuous-wave ultrasonic modulation of scattered laser light to image objects in turbid media

Wang, Lihong and Jacques, Steven L. and Zhao, Xuemei (1995) Continuous-wave ultrasonic modulation of scattered laser light to image objects in turbid media. Optics Letters, 20 (6). pp. 629-631. ISSN 0146-9592. doi:10.1364/OL.20.000629. https://resolver.caltech.edu/CaltechAUTHORS:20160614-110751953

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Abstract

Continuous-wave ultrasonic modulation of scattered laser light has been used to image objects in tissue-simulating turbid media for what is to our knowledge the first time. The ultrasound wave focused into the turbid media modulates the laser light passing through the ultrasonic focal zone. The modulated laser light collected by a photomultiplier tube reflects the local mechanical and optical properties in the focal zone. Buried objects are located with millimeter resolution by scanning and detecting alterations of the modulated optical signal. This technique has the potential to provide a noninvasive, nonionizing, inexpensive diagnostic tool for diseases such as breast cancer.

Item Type:

Article

Related URLs:

URL	URL Type	Description
http://dx.doi.org/10.1364/OL.20.000629	DOI	Article
https://www.osapublishing.org/ol/abstract.cfm?uri=ol-20-6-629	Publisher	Article

ORCID:

Author	ORCID
Wang, Lihong	0000-0001-9783-4383

Additional Information:

© 1995 Optical Society of America. Received October 19, 1994. We thank L. Eppich for proofreading the manuscript and D. Liu for experimental assistance. This research was supported in part by the University of Texas M. D. Anderson Cancer Center, the Whitaker Foundation, the U.S. Air Force Office of Scientific Research, the U.S. Department of Energy, and the National Institutes of Health.

Funders:

Funding Agency	Grant Number
University of Texas	UNSPECIFIED
Whitaker Foundation	UNSPECIFIED
Air Force Office of Scientific Research (AFOSR)	UNSPECIFIED
Department of Energy (DOE)	UNSPECIFIED
NIH	UNSPECIFIED

Issue or Number:

DOI:

10.1364/OL.20.000629

Record Number:

CaltechAUTHORS:20160614-110751953

Persistent URL:

https://resolver.caltech.edu/CaltechAUTHORS:20160614-110751953

Official Citation:

L. Wang, S. Jacques, and X. Zhao, "Continuous-wave ultrasonic modulation of scattered laser light to image objects in turbid media," Opt. Lett. 20, 629-631 (1995)

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No commercial reproduction, distribution, display or performance rights in this work are provided.

ID Code:

67912

Collection:

CaltechAUTHORS

Deposited By:

Tony Diaz

Deposited On:

14 Jun 2016 18:38

Last Modified:

11 Nov 2021 03:56

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