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Retroviral-Like Element in a Marine Invertebrate

Springer, Mark S. and Davidson, Eric H. and Britten, Roy J. (1991) Retroviral-Like Element in a Marine Invertebrate. Proceedings of the National Academy of Sciences of the United States of America, 88 (19). pp. 8401-8404. ISSN 0027-8424. PMCID PMC52516.

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Retroviral-like elements (RL elements) include retroviruses and long terminal repeat (LTR)-containing retrotransposons. We report the presence of sea urchin RL elements (termed SURL) in eight species of sea urchins and find that these RL elements belong to several subfamilies. The complete DNA sequence of one SURL element in Tripneustes gratilla is 5266 base pairs long, including 254-nucleotide-long identical long terminal repeats (LTRs). It contains a single open reading frame nearly 4 kilobases long including the gag and pol genes. Comparison of conserved DNA sequences of RL elements from different sea urchin species indicates that active elements have been inserting copies into echinoid genomes for at least 200 million years.

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Additional Information:Copyright © 1991 by National Academy of Sciences Contributed by Roy J. Britten, June 17, 1991 We thank R. F. Doolittle and Wen-Hsiung Li for programs and are grateful for a T. gratilla phage A library prepared by Gregory Dolecki at Kewalo Marine Laboratory, Hawaii. This work was supported by the Lucille P. Markey Charitable Trust and the National Institutes of Health. The sequence reported in this paper has been deposited in the GenBank data base (accession no. M75723). The publication costs of this article were defrayed in part by page charge payment. This article must therefore be hereby marked "advertisement" in accordance with 18 U.S.C. §1734 solely to indicate this fact.
Funding AgencyGrant Number
Lucille P. Markey Charitable TrustUNSPECIFIED
Subject Keywords:retrotransposon; retrovirus; long terminal repeat; echinoderm; mobile elements
Issue or Number:19
PubMed Central ID:PMC52516
Record Number:CaltechAUTHORS:SPRIpnas91
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Usage Policy:No commercial reproduction, distribution, display or performance rights in this work are provided.
ID Code:6818
Deposited By: Archive Administrator
Deposited On:23 Dec 2006
Last Modified:02 Oct 2019 23:36

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