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The Replication of Bacteriophage MS2: IV. RNA Components specifically associated with Infection

Kelly, Regis B. and Gould, James L. and Sinsheimer, Robert L. (1965) The Replication of Bacteriophage MS2: IV. RNA Components specifically associated with Infection. Journal of Molecular Biology, 11 (3). pp. 562-575. ISSN 0022-2836. doi:10.1016/S0022-2836(65)80011-0.

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Phage-specific RNA components synthesized in MS2-infected cells under conditions in which host RNA synthesis is suppressed have been characterized by ultracentrifugal analysis. In addition to the 27 s viral RNA, three specific components, designated as 20 s, 15 s and 6 s are described. Physical properties and enzymic resistance of the 15 s and 6 s forms suggest that these are, at least partially, double-stranded. The 20 s component appears to be a single-stranded RNA, of different configuration from the viral form.

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Additional Information:© 1965 Elsevier Ltd. Received 26 October 1964. We are indebted to Dr Ray Valentine for valuable discussions and for assistance with the experiment with ultraviolet-irradiated cells. This research was supported in part by U.S. Public Health Service Grant RG6965.
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U.S. Public Health Service (USPHS)RG6965
Issue or Number:3
Record Number:CaltechAUTHORS:20160617-071023260
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Official Citation:Regis B. Kelly, James L. Gould, Robert L. Sinsheimer, The replication of bacteriophage MS2, Journal of Molecular Biology, Volume 11, Issue 3, 1965, Pages 562-575, ISSN 0022-2836, (
Usage Policy:No commercial reproduction, distribution, display or performance rights in this work are provided.
ID Code:68456
Deposited On:17 Jun 2016 19:14
Last Modified:11 Nov 2021 04:00

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