Dowell, Clifton E. and Sinsheimer, Robert L. (1966) The Process of Infection with Bacteriophage ΦX174: IX. Studies on the Physiology of Three ΦX174 Temperature-sensitive Mutants. Journal of Molecular Biology, 16 (2). pp. 374-386. ISSN 0022-2836. doi:10.1016/S0022-2836(66)80180-8. https://resolver.caltech.edu/CaltechAUTHORS:20160617-104411686
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Abstract
Representatives of three different complementing groups of ΦX174 temperature-sensitive mutants were studied for their ability to synthesize infective DNA at the restrictive temperature. One of the mutants showed normal or nearly normal production of infective single-stranded DNA (when compared with wild-type phage), whereas the other two failed to make any substantial amount. Double-stranded DNA components, of two densities in alkali, were made in all infections.
Item Type: | Article | |||||||||
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Additional Information: | © 1966 Elsevier Ltd. Received 16 September 1965, and in revised form 26 December 1965. We acknowledge the excellent technical assistance of Miss Alma Shafer. One of us (C.E.D.) was a postdoctoral fellow of the National Institutes of Health. This research was supported, in part, by research grant RG 6965 from the U.S. Public Health Service. | |||||||||
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Issue or Number: | 2 | |||||||||
DOI: | 10.1016/S0022-2836(66)80180-8 | |||||||||
Record Number: | CaltechAUTHORS:20160617-104411686 | |||||||||
Persistent URL: | https://resolver.caltech.edu/CaltechAUTHORS:20160617-104411686 | |||||||||
Official Citation: | Clifton E. Dowell, Robert L. Sinsheimer, The process of infection with bacteriophage ΦX174, Journal of Molecular Biology, Volume 16, Issue 2, 1966, Pages 374-386, ISSN 0022-2836, http://dx.doi.org/10.1016/S0022-2836(66)80180-8. (http://www.sciencedirect.com/science/article/pii/S0022283666801808) | |||||||||
Usage Policy: | No commercial reproduction, distribution, display or performance rights in this work are provided. | |||||||||
ID Code: | 68480 | |||||||||
Collection: | CaltechAUTHORS | |||||||||
Deposited By: | Ruth Sustaita | |||||||||
Deposited On: | 17 Jun 2016 18:09 | |||||||||
Last Modified: | 11 Nov 2021 04:00 |
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