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The Process of Infection with Bacteriophage ΦX174: IX. Studies on the Physiology of Three ΦX174 Temperature-sensitive Mutants

Dowell, Clifton E. and Sinsheimer, Robert L. (1966) The Process of Infection with Bacteriophage ΦX174: IX. Studies on the Physiology of Three ΦX174 Temperature-sensitive Mutants. Journal of Molecular Biology, 16 (2). pp. 374-386. ISSN 0022-2836. https://resolver.caltech.edu/CaltechAUTHORS:20160617-104411686

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Abstract

Representatives of three different complementing groups of ΦX174 temperature-sensitive mutants were studied for their ability to synthesize infective DNA at the restrictive temperature. One of the mutants showed normal or nearly normal production of infective single-stranded DNA (when compared with wild-type phage), whereas the other two failed to make any substantial amount. Double-stranded DNA components, of two densities in alkali, were made in all infections.


Item Type:Article
Related URLs:
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http://dx.doi.org/10.1016/S0022-2836(66)80180-8DOIArticle
http://www.sciencedirect.com/science/article/pii/S0022283666801808PublisherArticle
Additional Information:© 1966 Elsevier Ltd. Received 16 September 1965, and in revised form 26 December 1965. We acknowledge the excellent technical assistance of Miss Alma Shafer. One of us (C.E.D.) was a postdoctoral fellow of the National Institutes of Health. This research was supported, in part, by research grant RG 6965 from the U.S. Public Health Service.
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U.S. Public Health Service (USPHS)RG6965
Issue or Number:2
Record Number:CaltechAUTHORS:20160617-104411686
Persistent URL:https://resolver.caltech.edu/CaltechAUTHORS:20160617-104411686
Official Citation:Clifton E. Dowell, Robert L. Sinsheimer, The process of infection with bacteriophage ΦX174, Journal of Molecular Biology, Volume 16, Issue 2, 1966, Pages 374-386, ISSN 0022-2836, http://dx.doi.org/10.1016/S0022-2836(66)80180-8. (http://www.sciencedirect.com/science/article/pii/S0022283666801808)
Usage Policy:No commercial reproduction, distribution, display or performance rights in this work are provided.
ID Code:68480
Collection:CaltechAUTHORS
Deposited By: Ruth Sustaita
Deposited On:17 Jun 2016 18:09
Last Modified:03 Oct 2019 10:14

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