CaltechAUTHORS
  A Caltech Library Service

Behavior of Complex Knots in Single DNA Molecules

Bao, Xiaoyan R. and Lee, Heun Jin and Quake, Stephen R. (2003) Behavior of Complex Knots in Single DNA Molecules. Physical Review Letters, 91 (26). Art. No. 265506. ISSN 0031-9007. doi:10.1103/PhysRevLett.91.265506. https://resolver.caltech.edu/CaltechAUTHORS:BAOprl03

[img]
Preview
PDF - Published Version
See Usage Policy.

304kB
[img]
Preview
PDF (Erratum) - Erratum
See Usage Policy.

160kB
[img] Plain Text (README) - Supplemental Material
See Usage Policy.

1kB
[img] Video (WMV) (Video (MOV)) - Supplemental Material
See Usage Policy.

1MB
[img] Video (MPEG) (Video (MPEG)) - Supplemental Material
See Usage Policy.

2MB

Use this Persistent URL to link to this item: https://resolver.caltech.edu/CaltechAUTHORS:BAOprl03

Abstract

We used optical tweezers to tie individual DNA molecules in knots. Although these knots become highly localized under tension, they remain surprisingly mobile and undergo thermal diffusion with classical random walk statistics. The diffusion constants of knots with different complexities correlate with theoretical calculations of knot sizes. We show that this correlation can be explained by a simple hydrodynamical model of "self-reptation" of the knot along a polymer.


Item Type:Article
Related URLs:
URLURL TypeDescription
https://doi.org/10.1103/PhysRevLett.91.265506DOIUNSPECIFIED
Additional Information:©2003 The American Physical Society (Received 1 August 2003; published 31 December 2003) We thank D.E. Smith, P. Pieranski, M. Wang, and J. Su for helpful discussion, and J.-C. Meiners, K. Matthews, and A. Groisman for help with preliminary experiments. This work was funded in part by a grant from the Packard Foundation; X.R.B. thanks the Hertz Foundation for financial support. See Also: * Phys. Rev. Focus 12, story 25 <http://focus.aps.org/story/v12/st25> * Erratum: Xiaoyan R. Bao et al. Phys. Rev. Lett. 95, 199901 (E) (2005)
Subject Keywords:DNA; radiation pressure; thermal diffusion; molecular configurations
Issue or Number:26
DOI:10.1103/PhysRevLett.91.265506
Record Number:CaltechAUTHORS:BAOprl03
Persistent URL:https://resolver.caltech.edu/CaltechAUTHORS:BAOprl03
Usage Policy:No commercial reproduction, distribution, display or performance rights in this work are provided.
ID Code:6876
Collection:CaltechAUTHORS
Deposited By: Archive Administrator
Deposited On:30 Dec 2006
Last Modified:08 Nov 2021 20:37

Repository Staff Only: item control page