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Slow light for deep tissue imaging with ultrasound modulation

Zhang, Huiliang and Sabooni, Mahmood and Rippe, Lars and Kim, Chulhong and Kröll, Stefan and Wang, Lihong V. and Hemmer, Philip R. (2012) Slow light for deep tissue imaging with ultrasound modulation. Applied Physics Letters, 100 (13). Art. No. 131102. ISSN 0003-6951. PMCID PMC3326061. https://resolver.caltech.edu/CaltechAUTHORS:20160630-102054201

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Abstract

Slow light has been extensively studied for applications ranging from optical delay lines to single photon quantum storage. Here, we show that the time delay of slow-light significantly improves the performance of the narrowband spectral filters needed to optically detect ultrasound from deep inside highly scatteringtissue. We demonstrate this capability with a 9 cm thick tissue phantom, having 10 cm^(−1) reduced scattering coefficient, and achieve an unprecedented background-free signal. Based on the data, we project real time imaging at video rates in even thicker phantoms and possibly deep enough into real tissue for clinical applications like early cancer detection.


Item Type:Article
Related URLs:
URLURL TypeDescription
http://dx.doi.org/10.1063/1.3696307DOIArticle
http://scitation.aip.org/content/aip/journal/apl/100/13/10.1063/1.3696307PublisherArticle
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3326061PubMed CentralArticle
ORCID:
AuthorORCID
Wang, Lihong V.0000-0001-9783-4383
Additional Information:© 2012 American Institute of Physics. Received 6 February 2012; accepted 5 March 2012; published online 26 March 2012. S.K. was sponsored in part by the Swedish Research Council, the Knut & Alice Wallenberg Foundation, the Crafoord Foundation and the EC FP7 Contract No. 247743 (QuRep). L.V.W. was sponsored in part by National Institutes of Health grants R01 EB000712 and U54 CA136398.
Funders:
Funding AgencyGrant Number
Swedish Research CouncilUNSPECIFIED
Knut and Alice Wallenberg FoundationUNSPECIFIED
Crafoord FoundationUNSPECIFIED
European Commission247743
NIHR01 EB000712
NIHU54 CA136398
Issue or Number:13
PubMed Central ID:PMC3326061
Record Number:CaltechAUTHORS:20160630-102054201
Persistent URL:https://resolver.caltech.edu/CaltechAUTHORS:20160630-102054201
Official Citation:Slow light for deep tissue imaging with ultrasound modulation Zhang, Huiliang and Sabooni, Mahmood and Rippe, Lars and Kim, Chulhong and Kröll, Stefan and Wang, Lihong V. and Hemmer, Philip R., Applied Physics Letters, 100, 131102 (2012), DOI:http://dx.doi.org/10.1063/1.3696307
Usage Policy:No commercial reproduction, distribution, display or performance rights in this work are provided.
ID Code:68782
Collection:CaltechAUTHORS
Deposited By: Tony Diaz
Deposited On:06 Jul 2016 03:07
Last Modified:03 Oct 2019 10:16

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