Suzuki, Yuta and Tay, Jian Wei and Yang, Qiang and Wang, Lihong V. (2014) Continuous scanning of a time-reversed ultrasonically encoded optical focus by reflection-mode digital phase conjugation. Optics Letters, 39 (12). pp. 3441-3444. ISSN 0146-9592. PMCID PMC4138829. doi:10.1364/OL.39.003441. https://resolver.caltech.edu/CaltechAUTHORS:20160713-131030120
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Abstract
Time-reversed ultrasonically encoded (TRUE) optical focusing in turbid media was previously implemented using both analog and digital phase conjugation. The digital approach, in addition to its large energy gain, can improve the focal intensity and resolution by iterative focusing. However, performing iterative focusing at each focal position can be time-consuming. Here, we show that by gradually moving the focal position, the TRUE focal intensity is improved, as in iterative focusing at a fixed position, and can be continuously scanned to image fluorescent targets in a shorter time. In addition, our setup is, to the best of our knowledge, the first demonstration of TRUE focusing using a digital phase conjugate mirror in a reflection mode, which is more suitable for practical applications.
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Additional Information: | © 2014 Optical Society of America. Received December 12, 2013; revised April 7, 2014; accepted April 25, 2014; posted May 7, 2014 (Doc. ID 202448); published June 4, 2014. We thank James Ballard and Xiao Xu for editing the manuscript. This work was sponsored in part by National Institutes of Health grants DP1 EB016986 (NIH Director’s Pioneer Award) and R01 CA186567 (NIH Director’s Transformative Research Award). L.W. has a financial interest in Microphotoacoustics, Inc. and Endra, Inc., which, however, did not support this work. | ||||||||||||
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Issue or Number: | 12 | ||||||||||||
Classification Code: | (170.3880) Medical and biological imaging; (110.0113) Imaging through turbid media; (070.5040) Phase conjugation; (110.7050) Turbid media | ||||||||||||
PubMed Central ID: | PMC4138829 | ||||||||||||
DOI: | 10.1364/OL.39.003441 | ||||||||||||
Record Number: | CaltechAUTHORS:20160713-131030120 | ||||||||||||
Persistent URL: | https://resolver.caltech.edu/CaltechAUTHORS:20160713-131030120 | ||||||||||||
Official Citation: | Y. Suzuki, J. Tay, Q. Yang, and L. Wang, "Continuous scanning of a time-reversed ultrasonically encoded optical focus by reflection-mode digital phase conjugation," Opt. Lett. 39, 3441-3444 (2014) | ||||||||||||
Usage Policy: | No commercial reproduction, distribution, display or performance rights in this work are provided. | ||||||||||||
ID Code: | 69007 | ||||||||||||
Collection: | CaltechAUTHORS | ||||||||||||
Deposited By: | Tony Diaz | ||||||||||||
Deposited On: | 27 Jul 2016 17:12 | ||||||||||||
Last Modified: | 11 Nov 2021 04:07 |
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