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Pyrene-Wired Heme Domain Cytochrome P450 BM3 Electrodes

Udit, Andrew K. and Hill, Michael G. and Bittner, Garrett and Arnold, Frances H. and Gray, Harry B. (2006) Pyrene-Wired Heme Domain Cytochrome P450 BM3 Electrodes. ECS Meeting Abstracts, 501 (1). Abstract 9. ISSN 1091-8213.

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Cytochromes P450 (P450s) catalyze oxygenations of inert substrates under physiological conditions. Exploiting this activity in vitro would be greatly facilitated if reductants other than NADPH could be found. We are working on electrochemical methods for reduction of P450 from Bacillus megaterium (BM3), an attractive target for in vitro applications given its high turnover rates and broad substrate specificity [1].

Item Type:Article
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URLURL TypeDescription
Arnold, Frances H.0000-0002-4027-364X
Gray, Harry B.0000-0002-7937-7876
Additional Information:© 2006 The Electrochemical Society 207th ECS Meeting, MA2005-01 May 15-May 20, 2005, Quebec City, Canada We thank NSERC (Canada) (AKU), NSF (HBG), and David and Lucile Packard Foundation (MGH) for research support.
Funding AgencyGrant Number
Natural Sciences and Engineering Research Council of Canada (NSERC)UNSPECIFIED
David and Lucile Packard FoundationUNSPECIFIED
Issue or Number:1
Record Number:CaltechAUTHORS:UDIescm06
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Usage Policy:No commercial reproduction, distribution, display or performance rights in this work are provided.
ID Code:6910
Deposited By: Archive Administrator
Deposited On:02 Jan 2007
Last Modified:22 Nov 2019 09:58

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