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Full-Wave Iterative Image Reconstruction in Photoacoustic Tomography With Acoustically Inhomogeneous Media

Huang, Chao and Wang, Kun and Nie, Liming and Wang, Lihong V. and Anastasio, Mark A. (2013) Full-Wave Iterative Image Reconstruction in Photoacoustic Tomography With Acoustically Inhomogeneous Media. IEEE Transactions on Medical Imaging, 32 (6). pp. 1097-1110. ISSN 0278-0062. PMCID PMC4114232. doi:10.1109/TMI.2013.2254496.

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Existing approaches to image reconstruction in photoacoustic computed tomography (PACT) with acoustically heterogeneous media are limited to weakly varying media, are computationally burdensome, and/or cannot effectively mitigate the effects of measurement data incompleteness and noise. In this work, we develop and investigate a discrete imaging model for PACT that is based on the exact photoacoustic (PA) wave equation and facilitates the circumvention of these limitations. A key contribution of the work is the establishment of a procedure to implement a matched forward and backprojection operator pair associated with the discrete imaging model, which permits application of a wide-range of modern image reconstruction algorithms that can mitigate the effects of data incompleteness and noise. The forward and backprojection operators are based on the k-space pseudospectral method for computing numerical solutions to the PA wave equation in the time domain. The developed reconstruction methodology is investigated by use of both computer-simulated and experimental PACT measurement data.

Item Type:Article
Related URLs:
URLURL TypeDescription CentralArticle Paper
Wang, Lihong V.0000-0001-9783-4383
Anastasio, Mark A.0000-0002-3192-4172
Additional Information:© 2013 IEEE. Manuscript received December 21, 2012; revised February 14, 2013; accepted February 25, 2013. Date of publication March 22, 2013; date of current version May 29, 2013. This work was supported by the National Institutes of Health (NIH) under Award EB010049.
Funding AgencyGrant Number
NIHR01 EB010049
Issue or Number:6
PubMed Central ID:PMC4114232
Record Number:CaltechAUTHORS:20160727-101845822
Persistent URL:
Official Citation:C. Huang, K. Wang, L. Nie, L. V. Wang and M. A. Anastasio, "Full-Wave Iterative Image Reconstruction in Photoacoustic Tomography With Acoustically Inhomogeneous Media," in IEEE Transactions on Medical Imaging, vol. 32, no. 6, pp. 1097-1110, June 2013. doi: 10.1109/TMI.2013.2254496
Usage Policy:No commercial reproduction, distribution, display or performance rights in this work are provided.
ID Code:69246
Deposited By: Tony Diaz
Deposited On:27 Jul 2016 18:34
Last Modified:11 Nov 2021 04:11

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