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Aperture scanning Fourier ptychographic microscopy

Ou, Xiaoze and Chung, Jaebum and Horstmeyer, Roarke and Yang, Changhuei (2016) Aperture scanning Fourier ptychographic microscopy. Biomedical Optics Express, 7 (8). pp. 3140-3150. ISSN 2156-7085. PMCID PMC4986821. doi:10.1364/BOE.7.003140.

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Fourier ptychographic microscopy (FPM) is implemented through aperture scanning by an LCOS spatial light modulator at the back focal plane of the objective lens. This FPM configuration enables the capturing of the complex scattered field for a 3D sample both in the transmissive mode and the reflective mode. We further show that by combining with the compressive sensing theory, the reconstructed 2D complex scattered field can be used to recover the 3D sample scattering density. This implementation expands the scope of application for FPM and can be beneficial for areas such as tissue imaging and wafer inspection.

Item Type:Article
Related URLs:
URLURL TypeDescription CentralArticle
Chung, Jaebum0000-0003-3932-8428
Horstmeyer, Roarke0000-0002-2480-9141
Yang, Changhuei0000-0001-8791-0354
Additional Information:© 2016 Optical Society of America. Received 20 Apr 2016; revised 23 Jun 2016; accepted 17 Jul 2016; published 29 Jul 2016. The authors thank Haojiang Zhou and Hangwen Lu for discussions and help with experiments. The authors acknowledge funding support from FLUOROFM (grant no. R01 AI096226) and CII 2015 (grant no. 32070065).
Funding AgencyGrant Number
NIHR01 AI096226
Caltech Innovation Initiative (CI2)32070065
Issue or Number:8
Classification Code:OCIS codes: (180.0180) Microscopy; (090.1995) Digital holography; (110.6880) Three-dimensional image acquisition
PubMed Central ID:PMC4986821
Record Number:CaltechAUTHORS:20160729-151210898
Persistent URL:
Official Citation:Xiaoze Ou, Jaebum Chung, Roarke Horstmeyer, and Changhuei Yang, "Aperture scanning Fourier ptychographic microscopy," Biomed. Opt. Express 7, 3140-3150 (2016)
Usage Policy:No commercial reproduction, distribution, display or performance rights in this work are provided.
ID Code:69330
Deposited By: Tony Diaz
Deposited On:29 Jul 2016 23:01
Last Modified:25 Apr 2022 23:04

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