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Nucleotide Sequence of Cloned Rat Serum Albumin Messenger RNA

Sargent, Thomas D. and Yang, Maria and Bonner, James (1981) Nucleotide Sequence of Cloned Rat Serum Albumin Messenger RNA. Proceedings of the National Academy of Sciences of the United States of America, 78 (1). pp. 243-246. ISSN 0027-8424.

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The nucleotide sequences of the recombinant DNA inserts of three bacterial plasmid clones containing nearly all of the rat serum albumin mRNA have been determined. A statistical analysis of the nucleotide sequence reveals a pattern of repeated internal homology that confirms the "intragenic triplication" model of albumin evolution.

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Additional Information:Copyright © 1981 by the National Academy of Sciences Contributed by James F. Bonner, October 15, 1980 We thank R. Bruce Wallace for his helpful suggestions and T. Ikenaka for providing us with unpublished amino acid sequence data. This work was supported in part by Grants 5 T32 GM 07616 and GM 13762 awarded by the National Institute of General Medical Sciences. The publication costs of this article were defrayed in part by page charge payment. This article must therefore be hereby marked "advertisement" in accordance with 18 U. S. C. §1734 solely to indicate this fact.
Subject Keywords:molecular evolution; amino acid sequence; intragenic duplication
Issue or Number:1
Record Number:CaltechAUTHORS:SARpnas81
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Usage Policy:No commercial reproduction, distribution, display or performance rights in this work are provided.
ID Code:6945
Deposited By: Archive Administrator
Deposited On:03 Jan 2007
Last Modified:02 Oct 2019 23:37

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