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Energy enhancement in time-reversed ultrasonically encoded optical focusing using a photorefractive polymer

Suzuki, Yuta and Xu, Xiao and Lai, Puxiang and Wang, Lihong V. (2012) Energy enhancement in time-reversed ultrasonically encoded optical focusing using a photorefractive polymer. Journal of Biomedical Optics, 17 (8). Art. No. 080507. ISSN 1083-3668. PMCID PMC3418504. https://resolver.caltech.edu/CaltechAUTHORS:20160809-154049931

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Abstract

Time-reversed ultrasonically encoded (TRUE) optical focusing achieves light focusing into scattering media beyond one transport mean free path, which is desirable in biomedical optics. However, the focused optical energy needs to be increased for broad applications. Here, we report the use of a photorefractive polymer (PRP) as the phase conjugate mirror in TRUE optical focusing. The PRP boosted the focused optical energy by ∼40 times in comparison to the previously used photorefractive Bi_(12)SiO_(20) crystal. As a result, we successfully imaged absorbing objects embedded in the middle plane of a tissue-mimicking phantom having an optical thickness of 120 scattering mean free paths.


Item Type:Article
Related URLs:
URLURL TypeDescription
http://dx.doi.org/10.1117/1.JBO.17.8.080507DOIArticle
http://biomedicaloptics.spiedigitallibrary.org/article.aspx?articleid=1352552PublisherArticle
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3418504PubMed CentralArticle
ORCID:
AuthorORCID
Wang, Lihong V.0000-0001-9783-4383
Additional Information:© 2012 SPIE. Paper 12342L received May 31, 2012; revised manuscript received Jul. 19, 2012; accepted for publication Jul. 24, 2012; published online Aug. 14, 2012. We would like to thank Nitto Denko Technical@Oceanside, C.A. for helpful discussions and providing the PRP for this research. This work was sponsored by the National Academies Keck Futures Initiative grant IS 13. L.W. has a financial interest in Microphotoacoustics, Inc. and Endra, Inc., which, however did not support this work.
Funders:
Funding AgencyGrant Number
National Academies Keck Futures InitiativeIS 13
Subject Keywords:optical focusing; ultrasound modulation; optical imaging; guide star; phase conjugation; time reversal; photorefractive material
Issue or Number:8
PubMed Central ID:PMC3418504
Record Number:CaltechAUTHORS:20160809-154049931
Persistent URL:https://resolver.caltech.edu/CaltechAUTHORS:20160809-154049931
Official Citation:Suzuki Y, Xu X, Lai P, Wang LV; Energy enhancement in time-reversed ultrasonically encoded optical focusing using a photorefractive polymer. J. Biomed. Opt. 0001;17(8):080507-1-080507-3. doi:10.1117/1.JBO.17.8.080507
Usage Policy:No commercial reproduction, distribution, display or performance rights in this work are provided.
ID Code:69518
Collection:CaltechAUTHORS
Deposited By: Tony Diaz
Deposited On:10 Aug 2016 18:14
Last Modified:03 Oct 2019 10:23

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