Suzuki, Yuta and Xu, Xiao and Lai, Puxiang and Wang, Lihong V. (2012) Energy enhancement in time-reversed ultrasonically encoded optical focusing using a photorefractive polymer. Journal of Biomedical Optics, 17 (8). Art. No. 080507. ISSN 1083-3668. PMCID PMC3418504. https://resolver.caltech.edu/CaltechAUTHORS:20160809-154049931
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Abstract
Time-reversed ultrasonically encoded (TRUE) optical focusing achieves light focusing into scattering media beyond one transport mean free path, which is desirable in biomedical optics. However, the focused optical energy needs to be increased for broad applications. Here, we report the use of a photorefractive polymer (PRP) as the phase conjugate mirror in TRUE optical focusing. The PRP boosted the focused optical energy by ∼40 times in comparison to the previously used photorefractive Bi_(12)SiO_(20) crystal. As a result, we successfully imaged absorbing objects embedded in the middle plane of a tissue-mimicking phantom having an optical thickness of 120 scattering mean free paths.
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| Additional Information: | © 2012 SPIE. Paper 12342L received May 31, 2012; revised manuscript received Jul. 19, 2012; accepted for publication Jul. 24, 2012; published online Aug. 14, 2012. We would like to thank Nitto Denko Technical@Oceanside, C.A. for helpful discussions and providing the PRP for this research. This work was sponsored by the National Academies Keck Futures Initiative grant IS 13. L.W. has a financial interest in Microphotoacoustics, Inc. and Endra, Inc., which, however did not support this work. | ||||||||||||
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| Subject Keywords: | optical focusing; ultrasound modulation; optical imaging; guide star; phase conjugation; time reversal; photorefractive material | ||||||||||||
| Issue or Number: | 8 | ||||||||||||
| PubMed Central ID: | PMC3418504 | ||||||||||||
| Record Number: | CaltechAUTHORS:20160809-154049931 | ||||||||||||
| Persistent URL: | https://resolver.caltech.edu/CaltechAUTHORS:20160809-154049931 | ||||||||||||
| Official Citation: | Suzuki Y, Xu X, Lai P, Wang LV; Energy enhancement in time-reversed ultrasonically encoded optical focusing using a photorefractive polymer. J. Biomed. Opt. 0001;17(8):080507-1-080507-3. doi:10.1117/1.JBO.17.8.080507 | ||||||||||||
| Usage Policy: | No commercial reproduction, distribution, display or performance rights in this work are provided. | ||||||||||||
| ID Code: | 69518 | ||||||||||||
| Collection: | CaltechAUTHORS | ||||||||||||
| Deposited By: | Tony Diaz | ||||||||||||
| Deposited On: | 10 Aug 2016 18:14 | ||||||||||||
| Last Modified: | 03 Oct 2019 10:23 |
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