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Particulate Air Pollution: Possible Relevance in Asthma

Glovsky, M. M. and Miguel, Ann G. and Cass, Glen R. (1997) Particulate Air Pollution: Possible Relevance in Asthma. Allergy and Asthma Proceedings, 18 (3). pp. 163-166. ISSN 1088-5412. doi:10.2500/108854197778984392.

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The relative importance of air pollution in the pathogenesis of bronchial asthma has been of interest for several decades. Numerous studies on the role of gaseous air pollution containing ozone, nitrogen dioxide, sulfur dioxide, and carbon monoxide have been published. Very little attention has been focused on the role of respirable particles in the causation of asthma. In this article we summarize some of our ongoing investigations into the sources and composition of airborne particles in the Los Angeles and Pasadena atmosphere, including the search for biologically active particles that may induce asthma attacks. It is found that the urban atmosphere contains not only combustion-derived particles from diesel engine exhaust and gasoline-powered motor vehicle exhaust, but also particles formed from biological starting materials including plant debris, cigarette smoke, wood smoke, and meat smoke as well as tire debris containing some natural rubber and paved road dust. Paved road dust is a very complex mixture of particles including garden soil, tire dust, plant fragments, redeposited atmospheric particles of all types, and pollen fragments presumably ground up by passing traffic. We have shown previously that latex allergen can be extracted from tire dust, from roadside dust, and from respirable air samples taken at Los Angeles and Long Beach. At present, work is underway to identify the larger range of allergens that may be contributed by the entrainment of paved road dust into the atmosphere. The possible importance of pollen fragments present in paved road dust in very small particle sizes is discussed as well as their potential relevance in asthma.

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Additional Information:© 1997 OceanSide Publications. This article describes research underway for the California Air Resources Board and the South Coast Air Quality Management District.
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California Air Resources BoardUNSPECIFIED
South Coast Air Quality Management District (SCAQMD)UNSPECIFIED
Issue or Number:3
Record Number:CaltechAUTHORS:20160810-084749576
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Official Citation:Particulate Air Pollution: Possible Relevance in Asthma, Allergy and Asthma Proc., 18, 163-166, 1997, M.M. Glovsky, A.G. Miguel and G.R. Cass. DOI:
Usage Policy:No commercial reproduction, distribution, display or performance rights in this work are provided.
ID Code:69529
Deposited By: Ruth Sustaita
Deposited On:27 Mar 2018 20:34
Last Modified:11 Nov 2021 04:15

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