Yapici, Murat Kaya and Kim, Chulhong and Chang, Cheng-Chung and Jeon, Mansik and Guo, Zijian and Cai, Xin and Zou, Jun and Wang, Lihong V. (2012) Parallel acoustic delay lines for photoacoustic tomography. Journal of Biomedical Optics, 17 (11). Art. No. 116019. ISSN 1083-3668. PMCID PMC3491084. https://resolver.caltech.edu/CaltechAUTHORS:20160812-132252536
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Abstract
Achieving real-time photoacoustic (PA) tomography typically requires multi-element ultrasound transducer arrays and their associated multiple data acquisition (DAQ) electronics to receive PA waves simultaneously. We report the first demonstration of a photoacoustic tomography (PAT) system using optical fiber-based parallel acoustic delay lines (PADLs). By employing PADLs to introduce specific time delays, the PA signals (on the order of a few micro seconds) can be forced to arrive at the ultrasonic transducers at different times. As a result, time-delayed PA signals in multiple channels can be ultimately received and processed in a serial manner with a single-element transducer, followed by single-channel DAQ electronics. Our results show that an optically absorbing target in an optically scattering medium can be photoacoustically imaged using the newly developed PADL-based PAT system. Potentially, this approach could be adopted to significantly reduce the complexity and cost of ultrasonic array receiver systems.
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Additional Information: | © 2012 SPIE. Paper 12393 received Jun. 26, 2012; revised manuscript received Sep. 25, 2012; accepted for publication Oct. 1, 2012; published online Nov. 7, 2012. This work was supported in part by grants from the National Institutes of Health (R01 EB000712, R01 EB008085, R01 CA134539, U54 CA136398, and R01 CA157277). L. V. Wang has a financial interest in Microphotoacoustics, Inc. and in Endra, Inc., which, however, did not support this work. C. Kim and M. Jeon were supported by the University at Buffalo faculty start-up fund. C.-C. Chang and J. Zou were supported in part by a grant from the National Institutes of Health (U54 CA136398) and a grant from the National Science Foundation (CMMI-1131758). | ||||||||||||||
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Subject Keywords: | photoacoustic tomography; acoustic delay line: ultrasound transducer array: real-time imaging | ||||||||||||||
Issue or Number: | 11 | ||||||||||||||
PubMed Central ID: | PMC3491084 | ||||||||||||||
Record Number: | CaltechAUTHORS:20160812-132252536 | ||||||||||||||
Persistent URL: | https://resolver.caltech.edu/CaltechAUTHORS:20160812-132252536 | ||||||||||||||
Official Citation: | Yapici M, Kim C, Chang C, et al; Parallel acoustic delay lines for photoacoustic tomography. J. Biomed. Opt. 0001;17(11):116019-116019. doi:10.1117/1.JBO.17.11.116019 | ||||||||||||||
Usage Policy: | No commercial reproduction, distribution, display or performance rights in this work are provided. | ||||||||||||||
ID Code: | 69600 | ||||||||||||||
Collection: | CaltechAUTHORS | ||||||||||||||
Deposited By: | Tony Diaz | ||||||||||||||
Deposited On: | 12 Aug 2016 22:32 | ||||||||||||||
Last Modified: | 09 Mar 2020 13:19 |
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