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Fast voice-coil scanning optical-resolution photoacoustic microscopy

Wang, Lidai and Maslov, Konstantin and Yao, Junjie and Rao, Bin and Wang, Lihong V. (2011) Fast voice-coil scanning optical-resolution photoacoustic microscopy. Optics Letters, 36 (2). pp. 139-141. ISSN 0146-9592. PMCID PMC3086411. https://resolver.caltech.edu/CaltechAUTHORS:20160817-093425724

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Abstract

We developed a photoacoustic imaging system that has real-time imaging capability with optical resolution. The imaging system is capable of scanning at 20 Hz over a 9 mm range and up to 40 Hz over a 1 mm scanning range. A focused laser beam provides a lateral resolution of 3.4 μm as measured in an optically nonscattering medium. Flows of micrometer-sized carbon particles or whole blood in a silicone tube and individual red blood cells (RBCs) in mouse ear capillaries were also imaged in real time, demonstrating the capability to image highly dynamic processes in vivo at a micrometer-scale resolution.


Item Type:Article
Related URLs:
URLURL TypeDescription
http://dx.doi.org/10.1364/OL.36.000139DOIArticle
https://www.osapublishing.org/ol/abstract.cfm?uri=ol-36-2-139PublisherArticle
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3086411PubMed CentralArticle
ORCID:
AuthorORCID
Wang, Lihong V.0000-0001-9783-4383
Additional Information:© 2011 Optical Society of America. Received September 22, 2010; revised November 24, 2010; accepted November 27, 2010; posted December 13, 2010 (Doc. ID 135532); published January 6, 2011. We acknowledge the help of Li Li in the system design. This work was sponsored in part by National Institutes of Health (NIH) grants R01 EB000712, R01 EB008085, R01 CA134539, U54 CA136398, R01 EB010049, and 5P60 DK02057933. L. V. Wang has a financial interest in Microphotoacoustics, Inc. and Endra, Inc.; however, neither provided support for this work.
Funders:
Funding AgencyGrant Number
NIHR01 EB000712
NIHR01 EB008085
NIHR01 CA134539
NIHU54 CA136398
NIHR01 EB010049
NIH5P60 DK02057933
Issue or Number:2
Classification Code:OCIS codes: 170.3880, 170.5120, 180.5810
PubMed Central ID:PMC3086411
Record Number:CaltechAUTHORS:20160817-093425724
Persistent URL:https://resolver.caltech.edu/CaltechAUTHORS:20160817-093425724
Official Citation:Lidai Wang, Konstantin Maslov, Junjie Yao, Bin Rao, and Lihong V. Wang, "Fast voice-coil scanning optical-resolution photoacoustic microscopy," Opt. Lett. 36, 139-141 (2011)
Usage Policy:No commercial reproduction, distribution, display or performance rights in this work are provided.
ID Code:69701
Collection:CaltechAUTHORS
Deposited By: Tony Diaz
Deposited On:17 Aug 2016 16:42
Last Modified:03 Oct 2019 10:24

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