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Measurement of viscosity of adult zebrafish blood using a capillary pressure-driven viscometer

Kang, D. and Wang, W. and Lee, J. and Tai, Y. C. and Hsiai, T. K. (2015) Measurement of viscosity of adult zebrafish blood using a capillary pressure-driven viscometer. In: 18th International Conference on Solid-State Sensors, Actuators and Microsystems (TRANSDUCERS). IEEE , Piscataway, NJ, pp. 1661-1664. ISBN 978-1-4799-8955-3. https://resolver.caltech.edu/CaltechAUTHORS:20160826-105504418

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Abstract

This paper presents the first experimental work on the viscosity measurement of adult zebrafish whole blood using a capillary pressure-driven microfluidic viscometer. After the device calibration with water, the viscosity measurement of human whole blood was performed and in good agreement with published data, demonstrating the reliability of the device. Power law and Carreau-Yasuda rheological models were used to model the non-Newtonian behaviors of the human and zebrafish blood. Theoretical modeling and numerical algorithms were applied to determine the blood viscosity over a wide range of shear rates. The proposed approach is uniquely applicable for small sample volume (down to 1μL or less), and short measurement time (<3min). A wide range of shear rates is produced in a single test.


Item Type:Book Section
Related URLs:
URLURL TypeDescription
http://dx.doi.org/10.1109/TRANSDUCERS.2015.7181261 DOIArticle
ORCID:
AuthorORCID
Tai, Y. C.0000-0001-8529-106X
Hsiai, T. K.0000-0003-1734-0792
Additional Information:© 2015 IEEE. This work is supported by National Institutes of Health under award no. 7R01HL111437-03. The authors gratefully thank all the members of the Caltech Micromachining Lab and the UCLA Cardiovascular Engineering Research Laboratory for fruitful discussion.
Funders:
Funding AgencyGrant Number
NIH7R01HL111437-03
Subject Keywords:Capillary pressure-driven viscometer, human whole blood, adult zebrafish whole blood, non-Newtonian viscosity, empirical power law model, Carreau-Yasuda rheological model
Record Number:CaltechAUTHORS:20160826-105504418
Persistent URL:https://resolver.caltech.edu/CaltechAUTHORS:20160826-105504418
Official Citation:D. Kang, W. Wang, J. Lee, Y. C. Tai and T. K. Hsiai, "Measurement of viscosity of adult zebrafish blood using a capillary pressure-driven viscometer," 2015 Transducers - 2015 18th International Conference on Solid-State Sensors, Actuators and Microsystems (TRANSDUCERS), Anchorage, AK, 2015, pp. 1661-1664. doi: 10.1109/TRANSDUCERS.2015.7181261 URL: http://ieeexplore.ieee.org/stamp/stamp.jsp?tp=&arnumber=7181261&isnumber=7180834
Usage Policy:No commercial reproduction, distribution, display or performance rights in this work are provided.
ID Code:69971
Collection:CaltechAUTHORS
Deposited By: Tony Diaz
Deposited On:26 Aug 2016 18:07
Last Modified:25 Nov 2019 23:46

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