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Recognition of Ribosomal RNA Sites in DNA, I. Analysis of the E. coli System

Attardi, Giuseppe and Huang, Pien Chien and Kabat, Susan (1965) Recognition of Ribosomal RNA Sites in DNA, I. Analysis of the E. coli System. Proceedings of the National Academy of Sciences of the United States of America, 53 (6). pp. 1490-1498. ISSN 0027-8424. http://resolver.caltech.edu/CaltechAUTHORS:ATTpnas65a

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Abstract

The evidence recently presented of specific hybridization between bacterial ribosomal RNA and homologous DNA1-3 has indicated the possibility of a biochemical approach to the problem of the identification of ribosomal RNA sites in DNA. A difficulty in this approach is that while the specific role of the RNA in the hybridization is open to experimental test, the critical evidence of the unique involvement of presumptive DNA sites is not easily attainable.


Item Type:Article
Additional Information:Copyright © 1965 by National Academy of Sciences Communicated by Renato Dulbecco, March 22, 1965. We wish to thank Drs. J. Bonner and R. C. Huang for their gift of T4 DNA and pea embryo DNA, and Dr. A. G. DeBusk and E. Brandt for the Neurospora DNA. The capable assistance of Sandra Kiddy is gratefully acknowledged. These investigations were supported by a research grant from the National Institutes of Health (GM-11726).
Issue or Number:6
Record Number:CaltechAUTHORS:ATTpnas65a
Persistent URL:http://resolver.caltech.edu/CaltechAUTHORS:ATTpnas65a
Alternative URL:http://www.pnas.org/cgi/reprint/53/6/1490
Usage Policy:No commercial reproduction, distribution, display or performance rights in this work are provided.
ID Code:705
Collection:CaltechAUTHORS
Deposited By: Archive Administrator
Deposited On:15 Sep 2005
Last Modified:14 Nov 2014 19:18

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