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Monkey brain cortex imaging by photoacoustic tomography

Yang, Xinmai and Wang, Lihong V. (2008) Monkey brain cortex imaging by photoacoustic tomography. Journal of Biomedical Optics, 13 (4). Art. No. 044009. ISSN 1083-3668. doi:10.1117/1.2967907.

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Photoacoustic tomography (PAT) is applied to image the brain cortex of a monkey through the intact scalp and skull ex vivo. The reconstructed PAT image shows the major blood vessels on the monkey brain cortex. For comparison, the brain cortex is imaged without the scalp, and then imaged again without the scalp and skull. Ultrasound attenuation through the skull is also measured at various incidence angles. This study demonstrates that PAT of the brain cortex is capable of surviving the ultrasound signal attenuation and distortion caused by a relatively thick skull.

Item Type:Article
Related URLs:
URLURL TypeDescription
Wang, Lihong V.0000-0001-9783-4383
Additional Information:© 2008 SPIE. Paper 07471R received Nov. 25, 2007; revised manuscript received Mar. 3, 2008; accepted for publication Mar. 4, 2008; published online Aug. 20, 2008. This project was sponsored in part by National Institutes of Health Grant nos. R01 NS46214 and R01 EB000712.
Funding AgencyGrant Number
NIHR01 NS46214
NIHR01 EB000712
Subject Keywords:photoacoustics; imaging; monkey brain; tomography; skull
Issue or Number:4
Record Number:CaltechAUTHORS:20160923-155046420
Persistent URL:
Official Citation:Yang X, Wang LV; Monkey brain cortex imaging by photoacoustic tomography. J. Biomed. Opt. 0001;13(4):044009-044009-5
Usage Policy:No commercial reproduction, distribution, display or performance rights in this work are provided.
ID Code:70571
Deposited By: Tony Diaz
Deposited On:28 Sep 2016 23:35
Last Modified:11 Nov 2021 04:31

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