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Boundary conditions in photoacoustic tomography and image reconstruction

Wang, Lihong V. and Yang, Xinmai (2007) Boundary conditions in photoacoustic tomography and image reconstruction. Journal of Biomedical Optics, 12 (1). Art. No. 014027. ISSN 1083-3668. doi:10.1117/1.2709861.

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Recently, the field of photoacoustic tomography has experienced considerable growth. Although several commercially available pure optical imaging modalities, including confocal microscopy, two-photon microscopy, and optical coherence tomography, have been highly successful, none of these technologies can penetrate beyond ∼1mm into scattering biological tissues because all of them are based on ballistic and quasiballistic photons. Consequently, heretofore there has been a void in high-resolution optical imaging beyond this depth limit. Photoacoustic tomography has filled this void by combining high ultrasonic resolution and strong optical contrast in a single modality. However, it has been assumed in reconstruction of photoacoustic tomography until now that ultrasound propagates in a boundary-free infinite medium. We present the boundary conditions that must be considered in certain imaging configurations; the associated inverse solutions for image reconstruction are provided and validated by numerical simulation and experiment. Partial planar, cylindrical, and spherical detection configurations with a planar boundary are covered, where the boundary can be either hard or soft. Analogously to the method of images of sources, which is commonly used in forward problems, the ultrasonic detectors are imaged about the boundary to satisfy the boundary condition in the inverse problem.

Item Type:Article
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URLURL TypeDescription ItemConference Paper
Wang, Lihong V.0000-0001-9783-4383
Additional Information:© 2007 SPIE. Paper 06064R received Mar. 14, 2006; revised manuscript received Aug. 24, 2006; accepted for publication Oct. 8, 2006; published online Feb. 23, 2007. This paper is a revision of a paper presented at the SPIE conference on Photons Plus Ultrasound: Imaging and Sensing 2006, the Seventh Conference on Biomedical Thermoacoustics, Optoacoustics, and Acusto-optics, Jan. 2006, San Jose, California. The paper presented there appears unrefereed in SPIE Proceedings Vol. 6086. We thank Geng Ku for experimental assistance. This work is supported by the National Institutes of Health grants R01 NS46214 and R01 EB000712.
Funding AgencyGrant Number
NIHR01 NS46214
NIHR01 EB000712
Subject Keywords:boundary conditions; photoacoustic tomography; thermoacoustic tomography; image reconstruction; time reversal
Issue or Number:1
Record Number:CaltechAUTHORS:20160927-144537424
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Official Citation:Wang LV, Yang X; Boundary conditions in photoacoustic tomography and image reconstruction. J. Biomed. Opt. 0001;12(1):014027-014027-10
Usage Policy:No commercial reproduction, distribution, display or performance rights in this work are provided.
ID Code:70619
Deposited By: Tony Diaz
Deposited On:28 Sep 2016 22:43
Last Modified:11 Nov 2021 04:32

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