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A 16-channel 1.1mm^2 implantable seizure control SoC with sub-μW/channel consumption and closed-loop stimulation in 0.18µm CMOS

Shoaran, Mahsa and Shahshahani, Masoud and Farivar, Masoud and Almajano, Joyel and Shahshahani, Amirhossein and Schmid, Alexandre and Bragin, Anatol and Leblebici, Yusuf and Emami, Azita (2016) A 16-channel 1.1mm^2 implantable seizure control SoC with sub-μW/channel consumption and closed-loop stimulation in 0.18µm CMOS. In: VLSI Circuits Digest of Technical Papers, 2016 Symposium. IEEE , Piscataway, NJ, pp. 1-2. ISBN 978-1-5090-0634-2. http://resolver.caltech.edu/CaltechAUTHORS:20161004-110833478

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Abstract

We present a 16-channel seizure detection system-on-chip (SoC) with 0.92µW/channel power dissipation in a total area of 1.1mm^2 including a closed-loop neural stimulator. A set of four features are extracted from the spatially filtered neural data to achieve a high detection accuracy at minimal hardware cost. The performance is demonstrated by early detection and termination of kainic acid-induced seizures in freely moving rats and by offline evaluation on human intracranial EEG (iEEG) data. Our design improves upon previous works by over 40× reduction in power-area product per channel. This improvement is a key step towards integration of larger arrays with higher spatiotemporal resolution to further boost the detection accuracy.


Item Type:Book Section
Related URLs:
URLURL TypeDescription
http://dx.doi.org/10.1109/VLSIC.2016.7573557UNSPECIFIEDArticle
http://ieeexplore.ieee.org/document/7573557/PublisherArticle
ORCID:
AuthorORCID
Emami, Azita0000-0003-2608-9691
Additional Information:© 2016 Institute of Electrical and Electronics Engineers, Inc. Date Added to IEEE Xplore: 22 September 2016.
Record Number:CaltechAUTHORS:20161004-110833478
Persistent URL:http://resolver.caltech.edu/CaltechAUTHORS:20161004-110833478
Official Citation:M. Shoaran et al., "A 16-channel 1.1mm2 implantable seizure control SoC with sub-μW/channel consumption and closed-loop stimulation in 0.18µm CMOS," 2016 IEEE Symposium on VLSI Circuits (VLSI-Circuits), Honolulu, HI, USA, 2016, pp. 1-2. doi: 10.1109/VLSIC.2016.7573557
Usage Policy:No commercial reproduction, distribution, display or performance rights in this work are provided.
ID Code:70815
Collection:CaltechAUTHORS
Deposited By: Ruth Sustaita
Deposited On:04 Oct 2016 18:43
Last Modified:04 Oct 2016 21:55

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