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Imaging optically scattering objects with ultrasound-modulated optical tomography

Kothapalli, Sri-Rajasekhar and Sakadžić, Sava and Kim, Chulhong and Wang, Lihong V. (2007) Imaging optically scattering objects with ultrasound-modulated optical tomography. Optics Letters, 32 (16). pp. 2351-2353. ISSN 0146-9592. doi:10.1364/OL.32.002351.

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We show the feasibility of imaging objects having different optical scattering coefficients relative to the surrounding scattering medium using ultrasound-modulated optical tomography (UOT). While the spatial resolution depends on ultrasound parameters, the image contrast depends on the difference in scattering coefficient between the object and the surrounding medium. Experimental measurements obtained with a CCD-based speckle contrast detection scheme are in agreement with Monte Carlo simulations and analytical calculations. This study complements previous UOT experiments that demonstrated optical absorption contrast.

Item Type:Article
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Wang, Lihong V.0000-0001-9783-4383
Additional Information:© 2007 Optical Society of America. Received April 24, 2007; revised June 27, 2007; accepted July 2, 2007; posted July 6, 2007 (Doc. ID 82399); published August 2, 2007. We thank A. Garcia-Uribe for measuring optical properties of the tissue phantoms. This research is supported by the National Institute of Health grants R33 CA 094267 and R01 CA106728.
Funding AgencyGrant Number
NIHR33 CA 094267
NIHR01 CA106728
Issue or Number:16
Classification Code:OCIS codes: 030.6140, 110.6150, 110.7050, 110.7170, 170.3880
Record Number:CaltechAUTHORS:20161005-081635259
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Official Citation:Sri-Rajasekhar Kothapalli, Sava Sakadzic, Chulhong Kim, and Lihong V. Wang, "Imaging optically scattering objects with ultrasound-modulated optical tomography," Opt. Lett. 32, 2351-2353 (2007)
Usage Policy:No commercial reproduction, distribution, display or performance rights in this work are provided.
ID Code:70857
Deposited By: Tony Diaz
Deposited On:05 Oct 2016 16:22
Last Modified:11 Nov 2021 04:36

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