Mohr, Justin T. and Moore, Jared T. and Stoltz, Brian M. (2016) Enantioconvergent catalysis. Beilstein Journal of Organic Chemistry, 12 . pp. 2038-2045. ISSN 1860-5397 . PMCID PMC5082454. http://resolver.caltech.edu/CaltechAUTHORS:20161006-142747894
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Abstract
An enantioconvergent catalytic process has the potential to convert a racemic starting material to a single highly enantioenriched product with a maximum yield of 100%. Three mechanistically distinct approaches to effecting enantioconvergent catalysis are identified, and recent examples of each are highlighted. These processes are compared to related, non-enantioconvergent methods.
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| Additional Information: | © 2016 Mohr et al.; licensee Beilstein-Institut. This is an Open Access article under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. The license is subject to the Beilstein Journal of Organic Chemistry terms and conditions: (http://www.beilstein-journals.org/bjoc) Received: 29 July 2016. Accepted: 25 August 2016. Published: 16 September 2016. This article is part of the Thematic Series "Strategies in asymmetric catalysis". Guest Editor: T. P. Yoon. This publication is supported in part by the NIH-NIGMS (R01GM080269), Amgen, Eli Lilly (predoctoral fellowship to J. Mohr), and NIH 1F32 (GM116304-01) (postdoctoral fellowship to J. Moore). Additionally, we thank David C. Ebner for helpful discussions. | ||||||||||||
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| Subject Keywords: | asymmetric catalysis; enantioselectivity; synthetic methods | ||||||||||||
| PubMed Central ID: | PMC5082454 | ||||||||||||
| Record Number: | CaltechAUTHORS:20161006-142747894 | ||||||||||||
| Persistent URL: | http://resolver.caltech.edu/CaltechAUTHORS:20161006-142747894 | ||||||||||||
| Official Citation: | Enantioconvergent catalysis Justin T. Mohr, Jared T. Moore, Brian M. Stoltz Beilstein J. Org. Chem. 2016, 12, 2038–2045. | ||||||||||||
| Usage Policy: | No commercial reproduction, distribution, display or performance rights in this work are provided. | ||||||||||||
| ID Code: | 70928 | ||||||||||||
| Collection: | CaltechAUTHORS | ||||||||||||
| Deposited By: | Ruth Sustaita | ||||||||||||
| Deposited On: | 12 Oct 2016 22:38 | ||||||||||||
| Last Modified: | 22 Feb 2017 20:10 |
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