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Enantioconvergent catalysis

Mohr, Justin T. and Moore, Jared T. and Stoltz, Brian M. (2016) Enantioconvergent catalysis. Beilstein Journal of Organic Chemistry, 12 . pp. 2038-2045. ISSN 1860-5397. PMCID PMC5082454. doi:10.3762/bjoc.12.192.

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An enantioconvergent catalytic process has the potential to convert a racemic starting material to a single highly enantioenriched product with a maximum yield of 100%. Three mechanistically distinct approaches to effecting enantioconvergent catalysis are identified, and recent examples of each are highlighted. These processes are compared to related, non-enantioconvergent methods.

Item Type:Article
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URLURL TypeDescription CentralArticle
Mohr, Justin T.0000-0002-7005-3322
Stoltz, Brian M.0000-0001-9837-1528
Additional Information:© 2016 Mohr et al.; licensee Beilstein-Institut. This is an Open Access article under the terms of the Creative Commons Attribution License (, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. The license is subject to the Beilstein Journal of Organic Chemistry terms and conditions: ( Received: 29 July 2016. Accepted: 25 August 2016. Published: 16 September 2016. This article is part of the Thematic Series "Strategies in asymmetric catalysis". Guest Editor: T. P. Yoon. This publication is supported in part by the NIH-NIGMS (R01GM080269), Amgen, Eli Lilly (predoctoral fellowship to J. Mohr), and NIH 1F32 (GM116304-01) (postdoctoral fellowship to J. Moore). Additionally, we thank David C. Ebner for helpful discussions.
Funding AgencyGrant Number
NIH Postdoctoral Fellowship1F32 GM116304-01
Subject Keywords:asymmetric catalysis; enantioselectivity; synthetic methods
PubMed Central ID:PMC5082454
Record Number:CaltechAUTHORS:20161006-142747894
Persistent URL:
Official Citation:Enantioconvergent catalysis Justin T. Mohr, Jared T. Moore, Brian M. Stoltz Beilstein J. Org. Chem. 2016, 12, 2038–2045.
Usage Policy:No commercial reproduction, distribution, display or performance rights in this work are provided.
ID Code:70928
Deposited On:12 Oct 2016 22:38
Last Modified:14 Apr 2022 18:18

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