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In-vivo intravascular intervention with parylene micro-electrode to diagnose rupture-prone atherosclerotic plaque using electrical impedance spectroscopy

Luo, Y. and Zhang, Xiaoxiao and Packard, Rene and Rongsong, Li and Hsiai, Tzung and Liu, Yang and Tai, Yu-Chong (2016) In-vivo intravascular intervention with parylene micro-electrode to diagnose rupture-prone atherosclerotic plaque using electrical impedance spectroscopy. In: 29th International Conference on Micro Electro Mechanical Systems (MEMS), 2016. IEEE , Piscataway, NJ, pp. 307-310. ISBN 978-1-5090-1973-1. http://resolver.caltech.edu/CaltechAUTHORS:20161013-093518415

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Abstract

It is of great clinical interest to have easy and reliable diagnostic techniques to localize and identify vulnerable plaques. Here, an in-vivo, catheter-integrated and balloon-mounted Parylene-C micro electrode impedance sensor was developed for intra-vascular interrogation of atherosclerotic vulnerable plaques using Electrical Impedance spectroscopy (EIS). Successful in vivo experiments of the EIS device were demonstrated using high-fat-dieted New Zealand rabbits. The results showed that electrical impedance spectroscopy (EIS) with micro parylene electrodes is promising to distinguish unstable plaques.


Item Type:Book Section
Related URLs:
URLURL TypeDescription
http://dx.doi.org/10.1109/MEMSYS.2016.7421621DOIArticle
http://ieeexplore.ieee.org/xpls/icp.jsp?arnumber=7421621PublisherArticle
ORCID:
AuthorORCID
Tai, Yu-Chong0000-0001-8529-106X
Additional Information:© 2016 IEEE. The author would like to thank all Caltech MEMS group members for their fruitful discussions and suggestions.
Subject Keywords:Arteries, Atherosclerosis, Catheters, Electrodes, Impedance, Impedance measurement, Rabbits
Record Number:CaltechAUTHORS:20161013-093518415
Persistent URL:http://resolver.caltech.edu/CaltechAUTHORS:20161013-093518415
Official Citation:Y. Luo et al., "In-vivo intravascular intervention with parylene micro-electrode to diagnose rupture-prone atherosclerotic plaque using electrical impedance spectroscopy," 2016 IEEE 29th International Conference on Micro Electro Mechanical Systems (MEMS), Shanghai, 2016, pp. 307-310. doi: 10.1109/MEMSYS.2016.7421621
Usage Policy:No commercial reproduction, distribution, display or performance rights in this work are provided.
ID Code:71042
Collection:CaltechAUTHORS
Deposited By: Ruth Sustaita
Deposited On:13 Oct 2016 17:32
Last Modified:13 Oct 2016 17:32

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