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Oxygen generation by electrolysis to treat retinal ischemia

Scianmarello, Nicholas and Kang, Dongyang and Murali, Karthik and Cook, Colin and Han, Jeff and Humayun, Mark S. and Tai, Yu-Chong (2016) Oxygen generation by electrolysis to treat retinal ischemia. In: 29th International Conference on Micro Electro Mechanical Systems (MEMS), 2016. IEEE , Piscataway, NJ, pp. 399-402. ISBN 978-1-5090-1973-1.

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This paper reports the first electrolysis-based oxygen generation and transportation device for the treatment of retinal ischemia; containing an isolated biocompatible electrolyte and inductive power transfer for on-demand oxygen. A finite element model of the retina along with oxygen delivery data demonstrates the feasibility of the device. The estimated therapeutic window for the device was found to be 210 minutes for the light adapted retina, and 55 minutes for the dark adapted retina.

Item Type:Book Section
Related URLs:
URLURL TypeDescription
Cook, Colin0000-0002-6283-5105
Humayun, Mark S.0000-0002-5830-5208
Tai, Yu-Chong0000-0001-8529-106X
Additional Information:© 2016 IEEE. Date Added to IEEE Xplore: 29 February 2016. This work is funded by the National Institute of Health. The authors are grateful to all members of the Caltech Micromachining Laboratory and USC Eye Institute for their help.
Funding AgencyGrant Number
Subject Keywords: Decision support systems, Oxygen, Electrochemical processes, Retina, Micromechanical devices, Electrodes, Hafnium
Record Number:CaltechAUTHORS:20161013-103650860
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Official Citation:N. Scianmarello et al., "Oxygen generation by electrolysis to treat retinal ischemia," 2016 IEEE 29th International Conference on Micro Electro Mechanical Systems (MEMS), Shanghai, 2016, pp. 399-402. doi: 10.1109/MEMSYS.2016.7421645
Usage Policy:No commercial reproduction, distribution, display or performance rights in this work are provided.
ID Code:71045
Deposited By: Ruth Sustaita
Deposited On:13 Oct 2016 18:03
Last Modified:09 Mar 2020 13:18

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