CaltechAUTHORS
  A Caltech Library Service

Visualization of human retinal capillary networks: a comparison of intensity, speckle-variance and phase-variance optical coherence tomography

Kim, Dae Yu and Fingler, Jeff and Werner, John S. and Schwartz, Daniel M. and Fraser, Scott E. and Zawadzki, Robert J. (2012) Visualization of human retinal capillary networks: a comparison of intensity, speckle-variance and phase-variance optical coherence tomography. In: Optical Coherence Tomography and Coherence Domain Optical Methods in Biomedicine XVI. Proceedings of SPIE. No.8213. Society of Photo-Optical Instrumentation Engineers (SPIE) , Bellingham, WA, Art. No. 821307. ISBN 978-0-8194-8856-5. http://resolver.caltech.edu/CaltechAUTHORS:20161101-080501256

[img] PDF - Published Version
See Usage Policy.

1741Kb

Use this Persistent URL to link to this item: http://resolver.caltech.edu/CaltechAUTHORS:20161101-080501256

Abstract

We evaluate methods to visualize human retinal micro-circulation in vivo by standard intensity-based optical coherence tomography (OCT), speckle-variance optical coherence tomography (svOCT), and phase-variance optical coherence tomography (pvOCT). En face projection views created from the same volumetric data set of the human retina using all three data processing methods are created and compared. Additionally we used support vector machine (SVM) based semi-automatic segmentation to generate en face projection views of individual retinal layers. The layers include: first, the whole inner retina (from the nerve fiber layer to the outer nuclear layer), and second, from the ganglion cell layer to the outer nuclear layer. Finally, we compare the retinal vasculature images processed from the three OCT techniques and fluorescein angiography (FA).


Item Type:Book Section
Related URLs:
URLURL TypeDescription
http://dx.doi.org/10.1117/12.906940DOIArticle
http://proceedings.spiedigitallibrary.org/proceeding.aspx?articleid=1275496PublisherArticle
ORCID:
AuthorORCID
Fraser, Scott E.0000-0002-5739-4026
Additional Information:© 2012 SPIE Society of Photo-Optical Instrumentation Engineers. This research was partially supported by National Eye Institute (EY 014743), Research to Prevent Blindness (RPB), Beckman Institute, and That Man May See Foundation.
Funders:
Funding AgencyGrant Number
National Eye Institute EY 014743
Research to Prevent BlindnessUNSPECIFIED
Caltech Beckman InstituteUNSPECIFIED
That Man May See FoundationUNSPECIFIED
Subject Keywords:Optical coherence tomography; Phase contrast technique; Imaging system; Medical optics instrumentation
Record Number:CaltechAUTHORS:20161101-080501256
Persistent URL:http://resolver.caltech.edu/CaltechAUTHORS:20161101-080501256
Official Citation:Dae Yu Kim ; Jeff Fingler ; John S. Werner ; Daniel M. Schwartz ; Scott E. Fraser ; Robert J. Zawadzki; Visualization of human retinal capillary networks: a comparison of intensity, speckle-variance and phase-variance optical coherence tomography. Proc. SPIE 8213, Optical Coherence Tomography and Coherence Domain Optical Methods in Biomedicine XVI, 821307 (February 9, 2012); doi:10.1117/12.906940.
Usage Policy:No commercial reproduction, distribution, display or performance rights in this work are provided.
ID Code:71649
Collection:CaltechAUTHORS
Deposited By: Ruth Sustaita
Deposited On:01 Nov 2016 17:28
Last Modified:01 Nov 2016 17:28

Repository Staff Only: item control page