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In vivo three-dimensional photoacoustic tomography of a whole mouse head

Song, Kwang Hyun and Stoica, George and Wang, Lihong V. (2006) In vivo three-dimensional photoacoustic tomography of a whole mouse head. Optics Letters, 31 (16). pp. 2453-2455. ISSN 0146-9592. http://resolver.caltech.edu/CaltechAUTHORS:20161109-154531350

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Abstract

An in vivo photoacoustic imaging system was designed and implemented to image the entire small animal head. A special scanning gantry was designed to enable in vivo imaging in coronal cross sections with high contrast and good spatial resolution for the first time to our knowledge. By use of a 2.25 MHz ultrasonic transducer with a 6 mm diameter active element, an in-plane radial resolution of ∼312  µm was achieved. Deeply seated arterial and venous vessels in the head measuring up to 1.7 cm in diameter were simultaneously imaged in vivo with 804 nm wavelength laser excitation of photoacoustic waves.


Item Type:Article
Related URLs:
URLURL TypeDescription
http://dx.doi.org/10.1364/OL.31.002453DOIArticle
https://www.osapublishing.org/ol/abstract.cfm?uri=ol-31-16-2453PublisherArticle
ORCID:
AuthorORCID
Wang, Lihong V.0000-0001-9783-4383
Additional Information:© 2006 Optical Society of America. Received April 4, 2006; revised May 15, 2006; accepted May 17, 2006; posted May 26, 2006 (Doc. ID 69679); published July 25, 2006. We thank Jung-Taek Oh, Meng-Lin Li, Konstantin Maslov, Geng Ku, and Xueyi Xie for technical assistance and Sergiu V. Similache for assistance with animal handling. The project was sponsored by National Institutes of Health grants R01 EB000712 and R01 NS46214.
Funders:
Funding AgencyGrant Number
NIHR01 EB000712
NIHR01 NS46214
Classification Code:OCIS codes: 170.5120, 170.3880, 170.0110
Record Number:CaltechAUTHORS:20161109-154531350
Persistent URL:http://resolver.caltech.edu/CaltechAUTHORS:20161109-154531350
Official Citation:Kwang Hyun Song, George Stoica, and Lihong V. Wang, "In vivo three-dimensional photoacoustic tomography of a whole mouse head," Opt. Lett. 31, 2453-2455 (2006)
Usage Policy:No commercial reproduction, distribution, display or performance rights in this work are provided.
ID Code:71899
Collection:CaltechAUTHORS
Deposited By: Tony Diaz
Deposited On:09 Nov 2016 23:51
Last Modified:09 Nov 2016 23:51

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