A Caltech Library Service

Helix-dependent Spin Filtering through the DNA Duplex

Zwang, Theodore J. and Hürlimann, Sylvia and Hill, Michael G. and Barton, Jacqueline K. (2016) Helix-dependent Spin Filtering through the DNA Duplex. Journal of the American Chemical Society, 138 (48). pp. 15551-15554. ISSN 0002-7863. PMCID PMC5175457. doi:10.1021/jacs.6b10538.

[img] PDF - Accepted Version
See Usage Policy.

[img] PDF (PubMed Central) - Accepted Version
See Usage Policy.

[img] PDF (Materials and methods, supplementary text, Figures S1 to S5, Table S1) - Supplemental Material
See Usage Policy.


Use this Persistent URL to link to this item:


Recent work suggests that electrons can travel through DNA and other chiral molecules in a spin-selective manner, but little is known about the origin of this spin selectivity. Here we describe experiments on magnetized DNA-modified electrodes to explore spin-selective electron transport through hydrated duplex DNA. Our results show that the two spins migrate through duplex DNA with different yield, and that spin selectivity requires charge transport through the DNA duplex. Significantly, shifting the same duplex DNA between right-handed B- and left-handed Z-forms leads to a diode-like switch in spin-selectivity; which spin moves more efficiently through the duplex depends upon the DNA helicity. With DNA, the supramolecular organization of chiral moieties, rather than the chirality of the individual monomers, determines the selectivity in spin, and thus a conformational change can switch the spin selectivity.

Item Type:Article
Related URLs:
URLURL TypeDescription Information CentralArticle
Zwang, Theodore J.0000-0002-6815-4482
Barton, Jacqueline K.0000-0001-9883-1600
Additional Information:© 2016 American Chemical Society. Publication Date (Web): 15 Nov 2016. We are grateful to the NIH (GM61077) and the Moore Foundation for their financial support. TJZ is also an NSF GRFP fellow (DGE-1144469). We thank Dr. Natalie Muren for discussions. We thank John Abendroth, Professor Paul Weiss, Elizabeth O’Brien, and Philip Bartels for providing gold-capped nickel surfaces. The authors declare no competing financial interest.
Funding AgencyGrant Number
Gordon and Betty Moore FoundationUNSPECIFIED
NSF Graduate Research FellowshipDGE-1144469
Issue or Number:48
PubMed Central ID:PMC5175457
Record Number:CaltechAUTHORS:20161117-080611089
Persistent URL:
Official Citation:Helix-Dependent Spin Filtering through the DNA Duplex Theodore J. Zwang, Sylvia Hürlimann, Michael G. Hill, and Jacqueline K. Barton Journal of the American Chemical Society 2016 138 (48), 15551-15554 DOI: 10.1021/jacs.6b10538
Usage Policy:No commercial reproduction, distribution, display or performance rights in this work are provided.
ID Code:72094
Deposited By: Tony Diaz
Deposited On:17 Nov 2016 17:47
Last Modified:07 Apr 2022 16:35

Repository Staff Only: item control page