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In Vivo Intraocular Pressure Measurements Using a Miniaturized Nanophotonics-enhanced Sensor Implant

Lee, Jeong Oen (2016) In Vivo Intraocular Pressure Measurements Using a Miniaturized Nanophotonics-enhanced Sensor Implant. In: 2016 Progress in Electromagnetic Research Symposium (PIERS). IEEE , Piscataway, NJ, p. 3939. ISBN 978-1-5090-6093-1.

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Surface Enhanced Raman Scattering (SERS) has a great potential to serve as a monitoring technology for biomolecules, but sensing biomolecules for practical purposes have remained challenging for two reasons. One of the challenges is securing SERS substrates with uniform spatial enhancement that is crucial for quantitative measurements, and the other is finding proper linker molecules that will promote the surface enhancement. To address these challenges, we have been developing a new approach of using highly sensitive surface enhanced Raman scattering (SERS) platform for glucose sensing. In the presentation, I will discuss the fabrication of high performance 3D SERS substrate based on straightforward, two successive wet chemical processes, with experimentally proven strong enhancement and excellent spatial uniformity as well as the use of new linker molecules for making glucose-specific SERS substrates and their use in performing quantitative glucose measurements. Glucose sensing results from different development stages will be discussed.

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Additional Information:© 2016 IEEE. Date Added to IEEE Xplore: 10 November 2016.
Record Number:CaltechAUTHORS:20161117-093922442
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Official Citation:Jeong Oen Lee, "In vivo intraocular pressure measurements using a miniaturized nanophotonics-enhanced sensor implant," 2016 Progress in Electromagnetic Research Symposium (PIERS), Shanghai, China, 2016, pp. 3939-3939. doi: 10.1109/PIERS.2016.7735483
Usage Policy:No commercial reproduction, distribution, display or performance rights in this work are provided.
ID Code:72109
Deposited By: Ruth Sustaita
Deposited On:17 Nov 2016 17:47
Last Modified:03 Oct 2019 16:14

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