A Proton Magnetic Resonance Study of The Interaction of Adenosine with Polyuridylic Acid: Evidence for Both Adenine-Uracil Base-Stacking and Base-Pairing

Bangerter, Benedict W. and Chan, Sunney I. (1968) A Proton Magnetic Resonance Study of The Interaction of Adenosine with Polyuridylic Acid: Evidence for Both Adenine-Uracil Base-Stacking and Base-Pairing. Proceedings of the National Academy of Sciences of the United States of America, 60 (4). pp. 1144-1151. ISSN 0027-8424. PMCID PMC224893. https://resolver.caltech.edu/CaltechAUTHORS:BANpnas68

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Abstract

We report here a proton magnetic resonance (pmr) study of the interaction of adenosine with polyuridylic acid in aqueous solution. The results of this study indicate that the mode of interaction is adenosine intercalation and adenine-uracil base-stacking above 26[degrees]C, and verifies that a triple-stranded complex which is stabilized by both adenine-uracil hydrogen-bonding and adenine-adenine base-stacking is formed below this temperature. Some information regarding the dynamics of these processes has also been obtained.

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Article

Related URLs:

URL	URL Type	Description
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC224893/	PubMed Central	Article
http://www.pnas.org/cgi/reprint/60/4/1144	Other	UNSPECIFIED
http://www.pnas.org/cgi/reprint/60/4/1144	Other	UNSPECIFIED

ORCID:

Author	ORCID
Chan, Sunney I.	0000-0002-5348-2723

Additional Information:

© 1968 by the National Academy of Sciences Communicated by Norman Davidson, May 15, 1968 This work was supported in part by grant GM-14523-02, U.S. Public Health Service. Noyes Laboratory of Chemical Physics, Contribution no. 3676.

Funders:

Funding Agency	Grant Number
NIH	GM-14523-02

Other Numbering System:

Other Numbering System Name	Other Numbering System ID
Arthur Amos Noyes Laboratory of Chemical Physics	3676

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PubMed Central ID:

PMC224893

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CaltechAUTHORS:BANpnas68

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https://resolver.caltech.edu/CaltechAUTHORS:BANpnas68

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723

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CaltechAUTHORS

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Deposited On:

20 Sep 2005

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02 Oct 2019 22:36

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